Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.34 |
| ▸ | MMP12 | P39900 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 6/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 6/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 6/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | MYC | P01106 | 1/20 | 0.32 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.31 |
| ▸ | TUBB | P07437 | 1/20 | 0.31 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.31 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.31 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.31 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.31 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.31 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.31 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28048750 | 0.80 | LMNA (0.68) | LMNASMN1; SMN2BACE1MAOAMAOB | |
| SCHEMBL16475557 | 0.72 | LMNA (0.79) | LMNABACE1MAOAMAOBMYC | |
| SCHEMBL21351777 | 0.66 | KCNN4 (0.47) | LMNASMN1; SMN2KCNN4MMP12ADRA2A | |
| SCHEMBL84185 | 0.66 | KCNN4 (0.47) | LMNASMN1; SMN2KCNN4MMP12ADRA2A | |
| SCHEMBL11244830 | 0.65 | KDM4E (0.46) | LMNA | |
| SCHEMBL6987368 | 0.65 | MAOA (0.37) | LMNAMAOAMAOB | |
| SCHEMBL13283781 | 0.65 | MAPT (0.58) | SMN1; SMN2ADRA2AADRA2BADRA2C | |
| SCHEMBL9566190 | 0.64 | KCNN4 (0.46) | LMNASMN1; SMN2KCNN4MMP12ADRA2A | |
| SCHEMBL351341 | 0.64 | ADRA2A (0.39) | SMN1; SMN2KCNN4MMP12ADRA2AADRA2B | |
| SCHEMBL6984753 | 0.64 | ELANE (0.33) | MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020189540-A1 | METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE | 中外製薬株式会社 | 2020-09-24 | — | — | WO | disclosed |