SCHEMBL2244563

SCHEMBL2244563

NCC(=O)NC(Cc1c[nH]cn1)C(=O)NC(Cc1ccccc1)C(=O)O.[Cu]

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MME P08473 3/20 0.45
ITGB3 P05106 2/20 0.45
ITGA2B P08514 2/20 0.45
SLC15A2 Q16348 1/20 0.43
GNPAT O15228 1/20 0.43
MMP2 P08253 1/20 0.43
MMP7 P09237 1/20 0.43
MMP9 P14780 1/20 0.43
MMP12 P39900 1/20 0.43
MMP13 P45452 1/20 0.43
ACE P12821 1/20 0.42
CPA1 P15085 1/20 0.42
ACE2 Q9BYF1 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30692732 0.99 MME (0.46) MMEITGB3ITGA2BSLC15A2GNPAT
SCHEMBL5598794 0.99 MME (0.46) MMEITGB3ITGA2BSLC15A2GNPAT
SCHEMBL5598789 0.99 MME (0.46) MMEITGB3ITGA2BSLC15A2GNPAT
SCHEMBL4589435 0.98 MME (0.45) MMEITGB3ITGA2BSLC15A2GNPAT
SCHEMBL7806530 0.91 SLC15A2 (0.54) ITGB3ITGA2BSLC15A2GNPAT
SCHEMBL7799086 0.91 SLC15A2 (0.54) ITGB3ITGA2BSLC15A2GNPAT
SCHEMBL8012953 0.91 SLC15A2 (0.54) ITGB3ITGA2BSLC15A2GNPAT
SCHEMBL9390320 0.91 SLC15A2 (0.54) ITGB3ITGA2BSLC15A2GNPAT
SCHEMBL31453803 0.91 SLC15A2 (0.49) MMEITGB3ITGA2BSLC15A2
SCHEMBL20783813 0.91 SLC15A2 (0.49) MMEITGB3ITGA2BSLC15A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110206790-A1 Antimicrobial Foamable Soaps OHSO CLEAN, INC 2011-08-25 US disclosed
EP-2350252-A2 ANTIMICROBIAL FOAMABLE SOAPS Ohso Clean, Inc. (US) 2011-08-03 EP disclosed
US-20100249042-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF EYELASHES AND EYEBROWS PROCYTE CORPORATION (US) 2010-09-30 US disclosed
WO-2010059366-A2 ANTIMICROBIAL FOAMABLE SOAPS OHSO CLEAN, INC. (US) 2010-05-27 WO disclosed
EP-1613302-B1 PRESERVED AND STABLE COMPOSITIONS CONTAINING PEPTIDE COPPER COMPLEXES AND METHODS RELATED THERETO PROCYTE CORP (US) 2009-12-23 EP disclosed
US-7179789-B2 Compositions and methods for treatment of rosacea PROCYTE CORPORATION (US) 2007-02-20 US disclosed
US-7128923-B2 Preserved and stable compositions containing peptide copper complexes and method related thereto PROCYTE CORPORATION (US) 2006-10-31 US disclosed
US-20060052287-A1 Polyethylene glycol - peptide copper complexes and compositions and methods related thereto PROCYTE CORPORATION (US) 2006-03-09 US disclosed
US-20050209130-A1 Compositions and methods for treatment of rosacea PROCYTE CORPORATION (US) 2005-09-22 US disclosed
US-20050197282-A1 for topical administration of peptide copper complex with corticosteroids, coal tar, anthralin, calcipotriene, and tazarotene; dermatology; cosmetics PROCYTE CORPORATION (US) 2005-09-08 US disclosed
US-6927206-B2 Compositions and methods for treatment of rosacea PROCYTE CORPORATION (US) 2005-08-09 US disclosed
US-6927205-B2 Compositions and methods for treatment of psoriasis PROCYTE CORPORATION (US) 2005-08-09 US disclosed
EP-0765152-B1 STIMULATION OF HAIR GROWTH BY PEPTIDE-COPPER COMPLEXES PROCYTE CORP (US) 2001-11-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050209130-A1 Compositions and methods for treatment of rosacea CUTA, AOC1, RCN1 MME 2453/4885ITGB3 4478/4885ITGA2B 4335/4885
US-20060052287-A1 Polyethylene glycol - peptide copper complexes and compositions and methods related thereto NGLY1, CUTA, TFRC MME 686/4885ITGB3 4140/4885ITGA2B 4545/4885
US-20100249042-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF EYELASHES AND EYEBROWS CUTA, TYR, EYA3 MME 1051/4885ITGB3 3811/4885ITGA2B 4303/4885
US-20050197282-A1 for topical administration of peptide copper complex with corticosteroids, coal tar, anthralin, calcipotriene, and tazarotene; dermatology; cosmetics PTH1R, TSLP, CYP27B1 MME 2077/4885ITGB3 4719/4885ITGA2B 4785/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.