SCHEMBL22448155

SCHEMBL22448155

Cc1ccccc1Cc1ccc(C2=CCC(F)(F)CC2)s1

nearest known ligand 0.31

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ SLC5A2 P31639 3/20 0.31
▸ ABCB11 O95342 1/20 0.31
▸ ADORA3 P0DMS8 1/20 0.31
▸ SLC5A1 P13866 1/20 0.31
▸ SLC6A4 P31645 1/20 0.31
▸ SLC6A3 Q01959 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22448159 0.78 LTA4H (0.40) SLC5A2SLC5A1
SCHEMBL22448153 0.76 CYP2A13 (0.35) —
SCHEMBL22570600 0.75 SLC5A1 (0.51) SLC5A2ABCB11ADORA3SLC5A1SLC6A4
SCHEMBL22448154 0.75 SLC5A1 (0.51) SLC5A2ABCB11ADORA3SLC5A1SLC6A4
SCHEMBL22448156 0.68 P2RX7 (0.32) —
SCHEMBL12185865 0.68 SLC5A2 (0.53) SLC5A2ABCB11ADORA3SLC5A1SLC6A4
SCHEMBL5973653 0.67 S1PR4 (0.36) SLC5A2
SCHEMBL22448133 0.67 HSD11B1 (0.33) SLC5A2SLC5A1SLC6A4SLC6A3
SCHEMBL13183761 0.66 PRMT6 (0.48) SLC6A4SLC6A3
SCHEMBL22448157 0.65 TRPV3 (0.34) SLC5A2SLC5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3712147-B1 SGLTS INHIBITOR AND APPLICATION THEREOF SHANGDONG DANHONG PHARMACEUTICAL CO LTD (CN) 2023-01-25 — — EP disclosed
US-10822365-B1 SGLTS inhibitor and application thereof SHANDONG DANHONG PHARMACEUTICAL CO., LTD. (CN) 2020-11-03 — — US disclosed
US-20200331950-A1 SGLTS INHIBITOR AND APPLICATION THEREOF SHANDONG DANHONG PHARMACEUTICAL CO., LTD. 2020-10-22 — — US disclosed
EP-3712147-A1 SGLTS INHIBITOR AND APPLICATION THEREOF Shangdong Danhong Pharmaceutical Co., Ltd. (CN) 2020-09-23 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10822365-B1 SGLTS inhibitor and application thereof SLC5A1, SLC5A2, SLC5A11 SLC5A2 2/4885ABCB11 135/4885ADORA3 3044/4885
US-20200331950-A1 SGLTS INHIBITOR AND APPLICATION THEREOF SLC5A1, SLC5A2, SLC5A11 SLC5A2 2/4885ABCB11 135/4885ADORA3 3044/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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