SCHEMBL224519

SCHEMBL224519

Brc1c2nc(c(Br)c3ccc(cc4nc(cc5ccc1[nH]5)C=C4)[nH]3)C=C2

nearest known ligand 0.48

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ STAT3 P40763 1/20 0.48
▸ STAT1 P42224 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL79329 0.95 STAT3 (0.50) STAT3STAT1
SCHEMBL8831500 0.95 STAT3 (0.50) STAT3STAT1
SCHEMBL5062037 0.95 STAT3 (0.53) STAT3STAT1
SCHEMBL5013665 0.86 STAT3 (0.71) STAT3STAT1
Phosphoric Acid SCHEMBL30944426 0.86 STAT3 (0.46) STAT3STAT1
SCHEMBL4168760 0.84 STAT3 (0.44) STAT3STAT1
SCHEMBL868308 0.83 STAT3 (0.48) STAT3STAT1
SCHEMBL5134031 0.82 STAT3 (0.74) STAT3STAT1
SCHEMBL2940532 0.82 STAT3 (0.74) STAT3STAT1
SCHEMBL30767176 0.82 STAT3 (0.74) STAT3STAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107805254-B Porphyrin micromolecular perovskite cathode buffer layer material and preparation method and application thereof 华南理工大学 2020-08-18 — — CN claimed
US-11495368-B2 Hydrophobic, conductive organic materials for metallic surfaces INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2022-11-08 — — US disclosed
CN-107805254-B Porphyrin micromolecular perovskite cathode buffer layer material and preparation method and application thereof 华南理工大学 2020-08-18 — — CN disclosed
US-10453584-B2 Hydrophobic, conductive organic materials for metallic surfaces INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2019-10-22 — — US disclosed
US-10256421-B2 Fusing porphyrins with polycyclic aromatic hydrocarbons and heterocycles for optoelectronic applications UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2019-04-09 — — US disclosed
US-20180122531-A1 HYDROPHOBIC, CONDUCTIVE ORGANIC MATERIALS FOR METALLIC SURFACES INTERNATIONAL BUSINESS MACHINES CORPORATION 2018-05-03 — — US disclosed
EP-2470543-B1 VISIBLE/NIR PHOTODETECTORS UNIV MICHIGAN REGENTS (US) 2017-07-26 — — EP disclosed
US-20170092883-A1 FUSING PORPHYRINS WITH POLYCYCLIC AROMATIC HYDROCARBONS AND HETEROCYCLES FOR OPTOELECTRONIC APPLICATIONS UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2017-03-30 — — US disclosed
US-20150318479-A1 Visible/Near-Infrared Porphyrin-Tape/C60 Organic Photodetectors UNIVERSITY OF SOUTHERN CALIFORNIA 2015-11-05 — — US disclosed
US-20150280149-A1 FUSING PORPHYRINS WITH POLYCYCLIC AROMATIC HYDROCARBONS AND HETEROCYCLES FOR OPTOELECTRONIC APPLICATIONS THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2015-10-01 — — US disclosed
US-7417142-B2 Chiral porphyrins, chiral metalloporphyrins, and methods for synthesis of the same THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION, INC. (US) 2008-08-26 — — US disclosed
US-20070123618-A1 Stepwise growth of oligomeric redox-active molecules on a surface without the use of protecting groups THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2007-05-31 — — US disclosed
WO-2007047925-A2 SWALLOWTAIL MOTIFS FOR IMPARTING WATER SOLUBILITY TO PORPHYRINIC COMPOUNDS NORTH CAROLINA STATE UNIVERSITY (US) 2007-04-26 — — WO disclosed
WO-2007025114-A2 STEPWISE GROWTH OF OLIGOMERIC REDOX-ACTIVE MOLECULES ON A SURFACE WITHOUT THE USE OF PROTECTING GROUPS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2007-03-01 — — WO disclosed
US-20060030718-A1 Cobalt-based catalysts for the cyclization of alkenes UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION 2006-02-09 — — US disclosed
US-6951935-B2 Heteroatom-substituted porphyrins and methods for synthesis of same UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2005-10-04 — — US disclosed
US-20050124596-A1 Chiral porphyrins, chiral metalloporphyrins, and methods for synthesis of the same UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION 2005-06-09 — — US disclosed
US-6849730-B2 Methods of making porphyrins and related compounds with Lewis acids NORTH CAROLINA STATE UNIVERSITY (US) 2005-02-01 — — US disclosed
US-20030236400-A1 Heteroatom-substituted porphyrins and methods for synthesis of same UNIVERSITY OF TENNESSEE RESEARCH CORPORATION 2003-12-25 — — US disclosed
US-20030096978-A1 Methods of making porphyrins and related compounds with Lewis acids NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2003-05-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150318479-A1 Visible/Near-Infrared Porphyrin-Tape/C60 Organic Photodetectors PAH, PPOX, AHR STAT3 4098/4885STAT1 4068/4885
US-20060030718-A1 Cobalt-based catalysts for the cyclization of alkenes PPOX, HCCS, ICOSLG STAT3 3817/4885STAT1 4312/4885
US-10256421-B2 Fusing porphyrins with polycyclic aromatic hydrocarbons and heterocycles for optoelectronic applications PPOX, HMBS, TYR STAT3 3947/4885STAT1 3941/4885
US-20150280149-A1 FUSING PORPHYRINS WITH POLYCYCLIC AROMATIC HYDROCARBONS AND HETEROCYCLES FOR OPTOELECTRONIC APPLICATIONS PPOX, HMBS, TYR STAT3 3965/4885STAT1 3858/4885
US-20030236400-A1 Heteroatom-substituted porphyrins and methods for synthesis of same PPOX, HMBS, UROD STAT3 4156/4885STAT1 3973/4885
US-20170092883-A1 FUSING PORPHYRINS WITH POLYCYCLIC AROMATIC HYDROCARBONS AND HETEROCYCLES FOR OPTOELECTRONIC APPLICATIONS PPOX, HMBS, TYR STAT3 3965/4885STAT1 3858/4885
US-20030096978-A1 Methods of making porphyrins and related compounds with Lewis acids DDT, LIG3, SHARPIN STAT3 3690/4885STAT1 4534/4885
US-20050124596-A1 Chiral porphyrins, chiral metalloporphyrins, and methods for synthesis of the same PPOX, PPIF, HMBS STAT3 2986/4885STAT1 3579/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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