Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | FABP3 | P05413 | 2/20 | 0.40 |
| ▸ | FABP4 | P15090 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.37 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
| ▸ | MERTK | Q12866 | 1/20 | 0.35 |
| ▸ | TOP1 | P11387 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22452447 | 0.90 | KMT2A (0.41) | LMNAKMT2AMEN1FABP3FABP4 | |
| SCHEMBL22453332 | 0.87 | LMNA (0.41) | LMNAKMT2AMEN1FABP3FABP4 | |
| SCHEMBL22453398 | 0.83 | KMT2A (0.37) | LMNAKMT2AMEN1FABP3FABP4 | |
| SCHEMBL22453441 | 0.81 | TDP1 (0.37) | LMNAKMT2AMEN1FABP3FABP4 | |
| SCHEMBL22452986 | 0.78 | AKR1C3 (0.40) | LMNAKMT2AMEN1FABP3FABP4 | |
| SCHEMBL22453074 | 0.77 | PARP1 (0.41) | LMNAKMT2AMEN1POLBMAPT | |
| SCHEMBL22453440 | 0.74 | TOP1 (0.39) | LMNAKMT2AMEN1MAPTHPGD | |
| SCHEMBL22720148 | 0.70 | MEN1 (0.62) | LMNAKMT2AMEN1FABP3FABP4 | |
| SCHEMBL22453360 | 0.70 | HTR2A (0.33) | KMT2AMEN1SCN9A | |
| SCHEMBL22453159 | 0.69 | PDE7A (0.43) | LMNAKMT2AMEN1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020190774-A1 | NOVEL SMALL MOLECULE INHIBITORS OF TEAD TRANSCRIPTION FACTORS | THE GENERAL HOSPITAL CORPORATION (US) | 2020-09-24 | — | — | WO | disclosed |