Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 10/20 | 0.57 |
| ▸ | CNR2 | P34972 | 3/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22452687 | 0.88 | EPHX2 (0.53) | EPHX2CNR2CNR1CYP2C9 | |
| SCHEMBL22453142 | 0.85 | EPHX2 (0.40) | EPHX2CNR2HIF1ACYP2C9 | |
| SCHEMBL22453545 | 0.83 | HPGD (0.52) | EPHX2HIF1AMAPTTHRB | |
| SCHEMBL22452572 | 0.81 | MAPT (0.45) | EPHX2HIF1ACYP2C9MAPT | |
| SCHEMBL22453417 | 0.79 | CYP11B1 (0.48) | EPHX2HIF1ACYP2C9MAPT | |
| SCHEMBL22453416 | 0.78 | HIF1A (0.42) | CNR2HIF1AMAPT | |
| SCHEMBL22453409 | 0.76 | HIF1A (0.49) | HIF1AMAPT | |
| SCHEMBL22453411 | 0.75 | SYK (0.39) | CNR2HIF1AMAPT | |
| SCHEMBL22453525 | 0.73 | MAPT (0.50) | EPHX2CNR2HIF1AMAPT | |
| SCHEMBL22452964 | 0.73 | NPC1 (0.43) | EPHX2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020190774-A1 | NOVEL SMALL MOLECULE INHIBITORS OF TEAD TRANSCRIPTION FACTORS | THE GENERAL HOSPITAL CORPORATION (US) | 2020-09-24 | — | — | WO | disclosed |