Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 15/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22452799 | 0.88 | EPHX2 (0.53) | EPHX2KDM4ELMNAP2RX7NPC1 | |
| SCHEMBL22452709 | 0.87 | LTC4S (0.40) | KDM4ELMNAP2RX7NPC1 | |
| SCHEMBL22453533 | 0.85 | EPHX2 (0.40) | EPHX2 | |
| SCHEMBL22453033 | 0.84 | PGR (0.40) | EPHX2KDM4ELMNAP2RX7NPC1 | |
| SCHEMBL22452975 | 0.83 | AURKA (0.36) | KDM4ELMNAP2RX7 | |
| SCHEMBL22453031 | 0.80 | PNLIP (0.37) | EPHX2 | |
| SCHEMBL22452982 | 0.79 | CYP2C9 (0.48) | EPHX2KDM4ELMNANPC1 | |
| SCHEMBL22452808 | 0.79 | CYP2C9 (0.48) | EPHX2KDM4ELMNANPC1 | |
| SCHEMBL22453446 | 0.75 | NPC1 (0.44) | EPHX2KDM4ELMNANPC1 | |
| SCHEMBL22453268 | 0.73 | EPHX2 (0.55) | EPHX2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020190774-A1 | NOVEL SMALL MOLECULE INHIBITORS OF TEAD TRANSCRIPTION FACTORS | THE GENERAL HOSPITAL CORPORATION (US) | 2020-09-24 | — | — | WO | disclosed |