Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTC4S | Q16873 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22453033 | 0.91 | PGR (0.40) | LTC4SLMNAKDM4ENPC1RAB9A | |
| SCHEMBL22453446 | 0.89 | NPC1 (0.44) | LTC4SLMNAKDM4ENPC1MAPT | |
| SCHEMBL22452997 | 0.87 | EPHX2 (0.40) | LMNAKDM4ENPC1P2RX7 | |
| SCHEMBL22453533 | 0.83 | EPHX2 (0.40) | GAAALDH1A1MEN1KMT2A | |
| SCHEMBL22452975 | 0.81 | AURKA (0.36) | LMNAKDM4ESMN1; SMN2ALDH1A1AURKA | |
| SCHEMBL22452481 | 0.80 | PGR (0.48) | LMNAKDM4ENPC1MAPTSMN1; SMN2 | |
| SCHEMBL22453031 | 0.77 | PNLIP (0.37) | — | |
| SCHEMBL22453425 | 0.76 | HIF1A (0.43) | LMNANPC1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL22452799 | 0.75 | EPHX2 (0.53) | LMNAKDM4ENPC1MAPTSMN1; SMN2 | |
| SCHEMBL22453260 | 0.73 | LTC4S (0.44) | LTC4SLMNAKDM4EMAPTAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020190774-A1 | NOVEL SMALL MOLECULE INHIBITORS OF TEAD TRANSCRIPTION FACTORS | THE GENERAL HOSPITAL CORPORATION (US) | 2020-09-24 | — | — | WO | disclosed |