Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | DHODH | Q02127 | 8/20 | 0.45 |
| ▸ | MEN1 | O00255 | 7/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | PARG | Q86W56 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22453760 | 0.93 | RAB9A (0.40) | RAB9ANPC1HTTALDH1A1NPSR1 | |
| SCHEMBL22453075 | 0.88 | DHODH (0.49) | RAB9ANPC1HTTALDH1A1NPSR1 | |
| SCHEMBL22453074 | 0.88 | PARP1 (0.41) | RAB9ANPC1HTTALDH1A1MEN1 | |
| SCHEMBL22452713 | 0.83 | DHODH (0.43) | RAB9ANPC1HTTALDH1A1NPSR1 | |
| SCHEMBL22453756 | 0.82 | CNR2 (0.49) | RAB9ANPC1HTTALDH1A1NPSR1 | |
| SCHEMBL22452986 | 0.79 | AKR1C3 (0.40) | RAB9ANPC1HTTALDH1A1MEN1 | |
| SCHEMBL22453159 | 0.76 | PDE7A (0.43) | NPC1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL22453641 | 0.75 | DHODH (0.55) | RAB9ANPC1HTTALDH1A1NPSR1 | |
| SCHEMBL22452671 | 0.75 | SLC6A4 (0.39) | HTTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL22452811 | 0.75 | HIF1A (0.52) | ALDH1A1MEN1KMT2AMAPTPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020190774-A1 | NOVEL SMALL MOLECULE INHIBITORS OF TEAD TRANSCRIPTION FACTORS | THE GENERAL HOSPITAL CORPORATION (US) | 2020-09-24 | — | — | WO | disclosed |