SCHEMBL22454367

SCHEMBL22454367

CCC(C)(C)CC(C)(C)CC(C)(C)C(=O)NCCN

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.33
RIPK1 Q13546 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10297996 0.81 RIPK1 (0.46) CNR1RIPK1
SCHEMBL19177061 0.80 CNR1 (0.48) CNR1RIPK1
SCHEMBL24064221 0.79
SCHEMBL24002319 0.79 RIPK1 (0.34) CNR1RIPK1
SCHEMBL21415415 0.77 RIPK1 (0.38) CNR1RIPK1
SCHEMBL20144634 0.77 GGT1 (0.33) RIPK1
SCHEMBL14684132 0.75 ALDH1A1 (0.34) CNR1RIPK1
SCHEMBL20813616 0.74 DGAT1 (0.31)
SCHEMBL9499386 0.74 CNR1 (0.34) CNR1RIPK1
SCHEMBL22061841 0.73 DNM1 (0.44) CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230346965-A1 ENEDIYNE CONJUGATES SYNAFFIX B.V. (NL) 2023-11-02 US disclosed
US-11547763-B2 Enediyne conjugates SYNAHIX B.V. (NL) 2023-01-10 US disclosed
US-20200297861-A1 ENEDIYNE CONJUGATES SYNAFFIX B.V. (NL) 2020-09-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200297861-A1 ENEDIYNE CONJUGATES ENY2, ZYX, TPD52L2 CNR1 3575/4885RIPK1 977/4885
US-20230346965-A1 ENEDIYNE CONJUGATES ENY2, ZYX, TPD52L2 CNR1 3575/4885RIPK1 977/4885
US-11547763-B2 Enediyne conjugates ENY2, ZYX, TPD52L2 CNR1 3575/4885RIPK1 977/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.