SCHEMBL20813616

SCHEMBL20813616

COC(=O)C(C)(C)CC(C)(C)C(=O)NCCN

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20144634 0.81 GGT1 (0.33)
SCHEMBL17574065 0.78 DGAT1 (0.44) DGAT1
SCHEMBL14684132 0.77 ALDH1A1 (0.34)
SCHEMBL20121856 0.76 EGLN1 (0.42) DGAT1
SCHEMBL20696336 0.75 DGAT1 (0.35) DGAT1
SCHEMBL16622294 0.75 MMP8 (0.38) DGAT1
SCHEMBL9499386 0.75 CNR1 (0.34)
SCHEMBL10297996 0.75 RIPK1 (0.46)
SCHEMBL22454367 0.74 CNR1 (0.33)
SCHEMBL8209299 0.74 ESRRG (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019051257-A2 METHODS FOR TREATING HEPATITIS B INFECTIONS ARBUTUS BIOPHARMA CORPORATION (CA) 2019-03-14 WO disclosed