Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | ACLY | P53396 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 1/20 | 0.39 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL855703 | 0.84 | ACLY (0.51) | ACLYPKMMAPTPOLBLMNA | |
| SCHEMBL20290537 | 0.81 | KMT2A (0.51) | ACLYPTGES2MEN1KMT2AMCL1 | |
| SCHEMBL15108250 | 0.80 | PLA2G7 (0.49) | BRD4PKMFFAR4KMT2A | |
| SCHEMBL12649965 | 0.79 | CA1 (0.43) | IDH1MAPTLMNAMEN1KMT2A | |
| SCHEMBL19693721 | 0.78 | ADRB3 (0.44) | ACLYPTGES2 | |
| SCHEMBL27182878 | 0.77 | FFAR4 (0.44) | BRD4PKMFFAR4IDH1MAPT | |
| SCHEMBL19303542 | 0.77 | PSIP1 (0.51) | BRD4MAPTPOLBLMNAMEN1 | |
| SCHEMBL24435816 | 0.76 | BRD4 (0.45) | BRD4PKMFFAR4IDH1MAPT | |
| SCHEMBL17917630 | 0.76 | CA2 (0.50) | BRD4IDH1MCL1KIF11 | |
| SCHEMBL13468525 | 0.74 | ALDH1A1 (0.50) | MAPTPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020191205-A1 | PI4-KINASE INHIBITORS AND METHODS OF USING THE SAME | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2020-09-24 | — | — | WO | disclosed |