Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.44 |
| ▸ | IDH1 | O75874 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17917630 | 0.86 | CA2 (0.50) | BRD4MCL1IDH1KIF11 | |
| SCHEMBL12601590 | 0.84 | LMNA (0.51) | LMNAMAPTMEN1KMT2A | |
| SCHEMBL19997238 | 0.81 | KMT2A (0.51) | MCL1LMNATP53MEN1KMT2A | |
| SCHEMBL15108250 | 0.80 | PLA2G7 (0.49) | BRD4PKMFFAR4PLA2G7KMT2A | |
| SCHEMBL12601596 | 0.79 | IDH1 (0.41) | BRD4IDH1MAPTALDH1A1MEN1 | |
| SCHEMBL13565046 | 0.79 | MAPT (0.55) | IDH1LMNAMAPTALDH1A1POLB | |
| SCHEMBL24435766 | 0.79 | LMNA (0.35) | MCL1LMNASMN1; SMN2 | |
| SCHEMBL10116355 | 0.78 | ALDH1A1 (0.69) | IDH1LMNAMAPTALDH1A1PLA2G7 | |
| SCHEMBL3833417 | 0.78 | PTGES2 (0.40) | MAPTPOLBKMT2A | |
| SCHEMBL19303542 | 0.77 | PSIP1 (0.51) | BRD4LMNAMAPTPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220153711-A1 | P14-Kinase Inhibitors and Methods of Using the Same | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2022-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220153711-A1 | P14-Kinase Inhibitors and Methods of Using the Same | PI4KB, PI4KA, PI4K2A | BRD4 155/4885MCL1 1636/4885IDH1 2318/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.