SCHEMBL22457528

SCHEMBL22457528

C[C@@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O)N(C)C(=O)[C@H](Cc1ccccc1)N(C)C(=O)OC(C)(C)C

nearest known ligand 0.49

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ACE P12821 12/20 0.49
REN P00797 1/20 0.48
MME P08473 7/20 0.47
CPA1 P15085 2/20 0.44
ACE2 Q9BYF1 2/20 0.44
CTSS P25774 1/20 0.44
CTSK P43235 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24435980 1.00 ACE (0.49) ACERENMMECPA1ACE2
SCHEMBL24435832 0.99 ACE (0.48) ACERENMMECPA1ACE2
SCHEMBL24435918 0.96 REN (0.49) ACERENMMECPA1ACE2
SCHEMBL22457554 0.95 REN (0.51) ACERENMMECPA1ACE2
SCHEMBL24435839 0.90 CTSS (0.51) ACEMMECTSSCTSK
SCHEMBL15566416 0.89 ACE (0.52) ACEMMECPA1ACE2CTSS
SCHEMBL19474651 0.89 ACE (0.52) ACEMMECPA1ACE2CTSS
SCHEMBL15566419 0.89 ACE (0.52) ACEMMECPA1ACE2CTSS
SCHEMBL22457519 0.87 REN (0.55) ACERENMMECPA1ACE2
SCHEMBL32681197 0.87 ACE (0.53) ACERENMMECPA1ACE2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12240871-B2 Method for producing peptide compound NISSAN CHEMICAL CORPORATION (JP) 2025-03-04 US disclosed
US-20220153777-A1 METHOD FOR PRODUCING PEPTIDE COMPOUND NISSAN CHEMICAL CORPORATION (JP) 2022-05-19 US disclosed
US-20220153777-A1 METHOD FOR PRODUCING PEPTIDE COMPOUND NISSAN CHEMICAL CORPORATION (JP) 2022-05-19 US disclosed
WO-2020189621-A1 METHOD FOR PRODUCING PEPTIDE COMPOUND 日産化学株式会社 2020-09-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12240871-B2 Method for producing peptide compound NGLY1, NPPA, NPEPPS ACE 982/4885REN 1579/4885MME 67/4885
US-20220153777-A1 METHOD FOR PRODUCING PEPTIDE COMPOUND NGLY1, NPPA, NPEPPS ACE 982/4885REN 1579/4885MME 67/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.