SCHEMBL24435918

SCHEMBL24435918

C[C@@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O)N(C)C(=O)[C@H](Cc1ccccc1)N(C)C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)N(C)C(=O)OC(C)(C)C

nearest known ligand 0.49

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
REN P00797 1/20 0.49
ACE P12821 12/20 0.46
CCKAR P32238 1/20 0.44
CCKBR P32239 1/20 0.44
OPRD1 P41143 1/20 0.44
MME P08473 5/20 0.44
CPA1 P15085 2/20 0.43
ACE2 Q9BYF1 2/20 0.43
CTSS P25774 1/20 0.41
CTSK P43235 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24435832 0.96 ACE (0.48) RENACECCKARCCKBROPRD1
SCHEMBL22457528 0.96 ACE (0.49) RENACEMMECPA1ACE2
SCHEMBL24435980 0.96 ACE (0.49) RENACEMMECPA1ACE2
SCHEMBL24435839 0.91 CTSS (0.51) ACEMMECTSSCTSK
SCHEMBL22457554 0.91 REN (0.51) RENACEMMECPA1ACE2
SCHEMBL22457519 0.89 REN (0.55) RENACEMMECPA1ACE2
SCHEMBL15566416 0.85 ACE (0.52) ACEMMECPA1ACE2CTSS
SCHEMBL19474651 0.85 ACE (0.52) ACEMMECPA1ACE2CTSS
SCHEMBL15566419 0.85 ACE (0.52) ACEMMECPA1ACE2CTSS
SCHEMBL22457492 0.85 REN (0.58) RENACEMMECPA1ACE2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12240871-B2 Method for producing peptide compound NISSAN CHEMICAL CORPORATION (JP) 2025-03-04 US disclosed
US-20220153777-A1 METHOD FOR PRODUCING PEPTIDE COMPOUND NISSAN CHEMICAL CORPORATION (JP) 2022-05-19 US disclosed
US-20220153777-A1 METHOD FOR PRODUCING PEPTIDE COMPOUND NISSAN CHEMICAL CORPORATION (JP) 2022-05-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12240871-B2 Method for producing peptide compound NGLY1, NPPA, NPEPPS REN 1579/4885ACE 982/4885CCKAR 1512/4885
US-20220153777-A1 METHOD FOR PRODUCING PEPTIDE COMPOUND NGLY1, NPPA, NPEPPS REN 1579/4885ACE 982/4885CCKAR 1512/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.