SCHEMBL24435839

SCHEMBL24435839

C[C@@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O)N(C)C(=O)[C@H](Cc1ccccc1)N(C)C(=O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C

nearest known ligand 0.51

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CTSS P25774 5/20 0.51
ACE P12821 5/20 0.51
CTSK P43235 4/20 0.51
CTSL P07711 2/20 0.48
CTSB P07858 2/20 0.48
PPARA Q07869 2/20 0.47
ITGB3 P05106 1/20 0.46
ITGA2B P08514 1/20 0.46
MME P08473 1/20 0.45
PPARG P37231 1/20 0.45
ATM Q13315 1/20 0.45
KMT2A Q03164 1/20 0.45
PTPN1 P18031 1/20 0.45
MAPK1 P28482 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24435918 0.91 REN (0.49) CTSSACECTSKMME
SCHEMBL24435832 0.91 ACE (0.48) CTSSACECTSKMME
SCHEMBL22457528 0.90 ACE (0.49) CTSSACECTSKMME
SCHEMBL24435980 0.90 ACE (0.49) CTSSACECTSKMME
SCHEMBL29670301 0.89 ACE (0.58) CTSSACECTSKCTSLCTSB
SCHEMBL22457554 0.85 REN (0.51) CTSSACECTSKCTSLCTSB
SCHEMBL24435952 0.85 ACE (0.58) CTSSACECTSKCTSLCTSB
SCHEMBL29670435 0.85 ACE (0.56) CTSSACECTSKCTSLCTSB
SCHEMBL24435840 0.83 ACE (0.50) ACEMME
SCHEMBL8706268 0.82 ACE (0.58) CTSSACECTSKCTSLCTSB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12240871-B2 Method for producing peptide compound NISSAN CHEMICAL CORPORATION (JP) 2025-03-04 US disclosed
US-20220153777-A1 METHOD FOR PRODUCING PEPTIDE COMPOUND NISSAN CHEMICAL CORPORATION (JP) 2022-05-19 US disclosed
US-20220153777-A1 METHOD FOR PRODUCING PEPTIDE COMPOUND NISSAN CHEMICAL CORPORATION (JP) 2022-05-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12240871-B2 Method for producing peptide compound NGLY1, NPPA, NPEPPS CTSS 1051/4885ACE 982/4885CTSK 656/4885
US-20220153777-A1 METHOD FOR PRODUCING PEPTIDE COMPOUND NGLY1, NPPA, NPEPPS CTSS 1051/4885ACE 982/4885CTSK 656/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.