SCHEMBL22457541

SCHEMBL22457541

CN[C@@H](Cc1ccccc1)C(=O)N(C)[C@@H](C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MME P08473 8/20 0.56
ACE P12821 11/20 0.55
ACE2 Q9BYF1 3/20 0.52
CPA1 P15085 2/20 0.52
FOLH1 Q04609 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22457555 0.94 MME (0.53) MMEACEACE2CPA1
Hydrochloric Acid SCHEMBL29670408 0.93 MME (0.52) MMEACEACE2CPA1
SCHEMBL29511665 0.84 MME (0.67) MMEACEACE2CPA1FOLH1
SCHEMBL24435840 0.83 ACE (0.50) MMEACEACE2CPA1
SCHEMBL25627017 0.83 MME (0.66) MMEACEACE2CPA1FOLH1
SCHEMBL13744198 0.81 HDAC3 (0.48) MMEACEACE2CPA1
SCHEMBL22457528 0.81 ACE (0.49) MMEACEACE2CPA1
SCHEMBL24435980 0.81 ACE (0.49) MMEACEACE2CPA1
SCHEMBL24435839 0.81 CTSS (0.51) MMEACE
SCHEMBL29670351 0.80 ABCB1 (0.52) MMEACEACE2CPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12240871-B2 Method for producing peptide compound NISSAN CHEMICAL CORPORATION (JP) 2025-03-04 US disclosed
US-20220153777-A1 METHOD FOR PRODUCING PEPTIDE COMPOUND NISSAN CHEMICAL CORPORATION (JP) 2022-05-19 US disclosed
US-20220153777-A1 METHOD FOR PRODUCING PEPTIDE COMPOUND NISSAN CHEMICAL CORPORATION (JP) 2022-05-19 US disclosed
WO-2020189621-A1 METHOD FOR PRODUCING PEPTIDE COMPOUND 日産化学株式会社 2020-09-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12240871-B2 Method for producing peptide compound NGLY1, NPPA, NPEPPS MME 67/4885ACE 982/4885ACE2 1436/4885
US-20220153777-A1 METHOD FOR PRODUCING PEPTIDE COMPOUND NGLY1, NPPA, NPEPPS MME 67/4885ACE 982/4885ACE2 1436/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.