SCHEMBL24435840

SCHEMBL24435840

C[C@@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O)N(C)C(=O)[C@H](Cc1ccccc1)N(C)C(=O)[C@@H](N)Cc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ACE P12821 7/20 0.50
MME P08473 3/20 0.50
OPRD1 P41143 5/20 0.47
OPRM1 P35372 4/20 0.47
OPRK1 P41145 1/20 0.47
CPA1 P15085 1/20 0.47
ACE2 Q9BYF1 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24435832 0.85 ACE (0.48) ACEMMEOPRD1CPA1ACE2
SCHEMBL24435980 0.83 ACE (0.49) ACEMMECPA1ACE2
SCHEMBL22457528 0.83 ACE (0.49) ACEMMECPA1ACE2
SCHEMBL24435839 0.83 CTSS (0.51) ACEMME
SCHEMBL22457541 0.83 MME (0.56) ACEMMECPA1ACE2
SCHEMBL24435918 0.82 REN (0.49) ACEMMEOPRD1CPA1ACE2
Phenylalanyltyrosine SCHEMBL3037096 0.79 MME (0.67) ACEMMEOPRD1OPRM1OPRK1
Phenylalanyltyrosine SCHEMBL4282059 0.79 MME (0.67) ACEMMEOPRD1OPRM1OPRK1
SCHEMBL8695556 0.79 MME (0.67) ACEMMEOPRD1OPRM1OPRK1
Phenylalanyltyrosine SCHEMBL31255162 0.79 MME (0.67) ACEMMEOPRD1OPRM1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12240871-B2 Method for producing peptide compound NISSAN CHEMICAL CORPORATION (JP) 2025-03-04 US disclosed
US-20220153777-A1 METHOD FOR PRODUCING PEPTIDE COMPOUND NISSAN CHEMICAL CORPORATION (JP) 2022-05-19 US disclosed
US-20220153777-A1 METHOD FOR PRODUCING PEPTIDE COMPOUND NISSAN CHEMICAL CORPORATION (JP) 2022-05-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12240871-B2 Method for producing peptide compound NGLY1, NPPA, NPEPPS ACE 982/4885MME 67/4885OPRD1 4389/4885
US-20220153777-A1 METHOD FOR PRODUCING PEPTIDE COMPOUND NGLY1, NPPA, NPEPPS ACE 982/4885MME 67/4885OPRD1 4389/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.