Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.49 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | PLK1 | P53350 | 1/20 | 0.45 |
| ▸ | CCR1 | P32246 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | PTAFR | P25105 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22441365 | 0.86 | TAS1R3 (0.50) | TAS1R3TAS1R1RAB9ANPC1ALOX15 | |
| SCHEMBL22441369 | 0.86 | TAS1R3 (0.50) | TAS1R3TAS1R1RAB9ANPC1ALOX15 | |
| SCHEMBL22457601 | 0.84 | ROCK1 (0.45) | TAS1R3TAS1R1HPGDCYP3A4 | |
| SCHEMBL22458106 | 0.82 | GRM4 (0.51) | RAB9ANPC1HTTHPGDKMT2A | |
| SCHEMBL22457822 | 0.80 | KMT2A (0.45) | RAB9ANPC1HPGDPOLBALDH1A1 | |
| SCHEMBL22457756 | 0.80 | PTAFR (0.47) | RAB9ANPC1POLBALDH1A1KMT2A | |
| SCHEMBL22458123 | 0.76 | RAB9A (0.45) | RAB9ANPC1HPGDALDH1A1 | |
| SCHEMBL22458087 | 0.75 | SMN1; SMN2 (0.52) | RAB9ANPC1HTTALDH1A1KMT2A | |
| SCHEMBL5007649 | 0.75 | ROCK2 (0.63) | TAS1R3TAS1R1MAPK1CYP3A4 | |
| SCHEMBL24177409 | 0.75 | ALDH1A1 (0.48) | RAB9ANPC1POLBALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220002280-A1 | COMPOUNDS AND METHODS OF USE | FERRO THERAPEUTICS INC (US) | 2022-01-06 | — | — | US | disclosed |
| US-11040964-B2 | Compounds and methods of use | Ferro Therapeutics, Inc. (US) | 2021-06-22 | — | — | US | disclosed |
| US-20200299283-A1 | COMPOUNDS AND METHODS OF USE | BRIDGEBIO PHARMA, INC. | 2020-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220002280-A1 | COMPOUNDS AND METHODS OF USE | AIFM2, GPX4, GPX1 | TAS1R3 3730/4885TAS1R1 3650/4885RAB9A 2446/4885 |
| US-20200299283-A1 | COMPOUNDS AND METHODS OF USE | AIFM2, GPX4, GPX1 | TAS1R3 3730/4885TAS1R1 3650/4885RAB9A 2446/4885 |
| US-11040964-B2 | Compounds and methods of use | AIFM2, GPX4, GPX1 | TAS1R3 3730/4885TAS1R1 3650/4885RAB9A 2446/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.