SCHEMBL22472268

SCHEMBL22472268

CCCCCCCCCCCCCCCCCCOc1cc(COC(=O)CCC(=O)O[C@H]2C[C@H](n3cc(C)c(=O)[nH]c3=O)O[C@@H]2CO)cc(OCCCCCCCCCCCCCCCCCC)c1OCCCCCCCCCCCCCCCCCC

nearest known ligand 0.51

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
RNASE1 P07998 1/20 0.51
TK2 O00142 4/20 0.51
SLC6A2 P23975 1/20 0.47
ABCG2 Q9UNQ0 3/20 0.45
ABCB1 P08183 1/20 0.45
TK1 P04183 1/20 0.42
CA12 O43570 1/20 0.42
CA5A P35218 1/20 0.42
CA7 P43166 1/20 0.42
CA5B Q9Y2D0 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16704789 0.95 TK2 (0.46) RNASE1TK2SLC6A2ABCG2ABCB1
SCHEMBL13963213 0.95 TK2 (0.46) RNASE1TK2SLC6A2ABCG2ABCB1
SCHEMBL13963223 0.87 TK2 (0.39) RNASE1TK2SLC6A2ABCG2ABCB1
SCHEMBL21078683 0.86 RNASE1 (0.56) RNASE1TK2SLC6A2TK1
SCHEMBL13963217 0.85 TK2 (0.48) RNASE1TK2SLC6A2ABCG2ABCB1
SCHEMBL8999382 0.84 TK2 (0.67) RNASE1TK2SLC6A2ABCG2ABCB1
SCHEMBL16573643 0.84 RNASE1 (0.41) RNASE1TK2SLC6A2ABCG2ABCB1
SCHEMBL16130869 0.84 RNASE1 (0.41) RNASE1TK2SLC6A2ABCG2ABCB1
SCHEMBL20518491 0.82 TK2 (0.41) RNASE1TK2ABCG2ABCB1TK1
SCHEMBL16349867 0.79 RNASE1 (0.71) RNASE1TK2SLC6A2ABCG2ABCB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240018180-A1 OLIGONUCLEOTIDE PRODUCTION METHOD AJINOMOTO CO., INC. (JP) 2024-01-18 US disclosed
EP-4293035-A1 OLIGONUCLEOTIDE PRODUCTION METHOD AJINOMOTO CO., INC. (JP) 2023-12-20 EP disclosed
WO-2020196890-A1 METHOD FOR PRODUCING OLIGONUCLEOTIDE HAVING PHOSPHOROTHIOATE SITE 味の素株式会社 2020-10-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240018180-A1 OLIGONUCLEOTIDE PRODUCTION METHOD RNGTT, NOX4, POLRMT RNASE1 711/4885TK2 121/4885SLC6A2 4651/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.