Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1970937 | 0.75 | TDO2 (0.54) | PTGS1PTGS2CYP1A1CYP1B1TDO2 | |
| SCHEMBL30560928 | 0.75 | TDO2 (0.54) | PTGS1PTGS2CYP1A1CYP1B1TDO2 | |
| SCHEMBL1970938 | 0.75 | TDO2 (0.54) | PTGS1PTGS2CYP1A1CYP1B1TDO2 | |
| SCHEMBL30560978 | 0.73 | PELI1 (0.42) | PTGS1PTGS2CYP1A1CYP1B1HTR2A | |
| SCHEMBL2097319 | 0.73 | PTGS2 (0.42) | PTGS1PTGS2NFE2L2HTR2AHTR2C | |
| SCHEMBL20125001 | 0.73 | PTGS1 (0.46) | PTGS1PTGS2NFE2L2CYP1A1CYP1B1 | |
| SCHEMBL2097320 | 0.73 | PTGS2 (0.42) | PTGS1PTGS2NFE2L2HTR2AHTR2C | |
| SCHEMBL13678718 | 0.71 | PTGS1 (0.43) | PTGS1PTGS2NFE2L2HTR2AHTR2C | |
| SCHEMBL18906997 | 0.71 | PTGS1 (0.43) | PTGS1PTGS2NFE2L2HTR2AHTR2C | |
| SCHEMBL18322085 | 0.71 | ALDH1A1 (0.50) | KDM4EMEN1MAPTHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200308114-A1 | BETA ADRENERGIC AGONIST AND METHODS OF USING THE SAME | CURASEN THERAPEUTICS, INC. | 2020-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200308114-A1 | BETA ADRENERGIC AGONIST AND METHODS OF USING THE SAME | ADRB2, ADRB1, ADRA2C | PTGS1 1368/4885PTGS2 1308/4885NFE2L2 2589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.