SCHEMBL22483136

SCHEMBL22483136

c1cc2sc3cncnc3c2cn1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 5/20 0.33
DYRK1A Q13627 2/20 0.32
CLK1 P49759 1/20 0.32
LIMK1 P53667 4/20 0.31
CDK5 Q00535 2/20 0.31
CDK5R1 Q15078 1/20 0.31
CHEK1 O14757 1/20 0.30
AURKA O14965 1/20 0.30
DAPK3 O43293 1/20 0.30
PRKD3 O94806 1/20 0.30
MAP4K4 O95819 1/20 0.30
PAK4 O96013 1/20 0.30
ABL1 P00519 1/20 0.30
RET P07949 1/20 0.30
PIM1 P11309 1/20 0.30
FGFR1 P11362 1/20 0.30
PRKACA P17612 1/20 0.30
FLT1 P17948 1/20 0.30
LTK P29376 1/20 0.30
GRK5 P34947 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22483133 0.87 KDM4E (0.36) CYP2A6DYRK1ACLK1LIMK1CDK5
SCHEMBL606019 0.79 LIMK1 (0.50) LIMK1CDK5CDK5R1
SCHEMBL11884999 0.78 LIMK1 (0.40) CYP2A6CLK1LIMK1TBK1
SCHEMBL17917464 0.77 EGFR (0.31) CLK1LIMK1
SCHEMBL11884982 0.77 CYP2A6 (0.42) CYP2A6DYRK1ALIMK1CDK5CHEK1
SCHEMBL26423650 0.77 HASPIN (0.40) CYP2A6DYRK1ACLK1LIMK1CDK5
SCHEMBL26423651 0.77 HASPIN (0.40) CYP2A6DYRK1ACLK1LIMK1CDK5
SCHEMBL26423745 0.76 EGFR (0.33) CYP2A6
SCHEMBL26423717 0.76 CYP2A6 (0.36) CYP2A6CLK1CDK5CDK5R1
SCHEMBL24270404 0.76 CYP2A6 (0.34) CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11760769-B2 Composition and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-09-19 US disclosed
US-11760769-B2 Composition and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-09-19 US disclosed
US-20220223794-A1 HETEROCYCLIC COMPOUND CONTAINING HETEROATOM SUBSTITUTED FLUORENE AND APPLICATION THEREOF Wuhan Tianma Microelectronics Co., Ltd. Shanghai Branch (CN) 2022-07-14 US disclosed
EP-4002509-A1 LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME Samsung Electronics Co., Ltd. (KR) 2022-05-25 EP disclosed
US-20210009616-A1 COMPOSITION AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD (KR) 2021-01-14 US disclosed
US-20200308201-A1 COMPOSITION AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-10-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220223794-A1 HETEROCYCLIC COMPOUND CONTAINING HETEROATOM SUBSTITUTED FLUORENE AND APPLICATION THEREOF NR0B2, FPR3, NPR3 CYP2A6 425/4885DYRK1A 785/4885CLK1 2296/4885
US-20200308201-A1 COMPOSITION AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, LEF1 CYP2A6 553/4885DYRK1A 4615/4885CLK1 1991/4885
US-20210009616-A1 COMPOSITION AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SLC39A14, ORC3, TIMM13 CYP2A6 3265/4885DYRK1A 2833/4885CLK1 1201/4885
US-11760769-B2 Composition and organic light-emitting device including the same CRY1, CRY2, LEF1 CYP2A6 553/4885DYRK1A 4615/4885CLK1 1991/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.