Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | MGAM | O43451 | 2/20 | 0.33 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.33 |
| ▸ | SI | P14410 | 2/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22492990 | 0.74 | DGAT1 (0.53) | KCNMA1MAPTGAAMGAMAMY1A | |
| SCHEMBL23638342 | 0.74 | DGAT1 (0.58) | KCNMA1MAPTRAB9AGAAMGAM | |
| SCHEMBL22492992 | 0.72 | — | — | |
| SCHEMBL10428733 | 0.68 | KCNMA1 (0.62) | KCNMA1MAPTRAB9AGAAMGAM | |
| SCHEMBL11440840 | 0.67 | KCNMA1 (0.61) | KCNMA1MAPTRAB9AGAAMGAM | |
| SCHEMBL4054573 | 0.67 | KCNMA1 (0.61) | KCNMA1RAB9AGAAMGAMAMY1A | |
| SCHEMBL24019555 | 0.66 | KCNMA1 (0.59) | KCNMA1MAPTRAB9AGAAMGAM | |
| SCHEMBL10428583 | 0.66 | KCNMA1 (0.59) | KCNMA1MAPTRAB9AGAAMGAM | |
| SCHEMBL11294103 | 0.64 | KCNMA1 (0.57) | KCNMA1MAPTRAB9AGAAMGAM | |
| SCHEMBL8000704 | 0.64 | HPGD (0.37) | MAPTRAB9AGAALMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021194908-A1 | MODIFIED DIPEPTIDE CLEAVASES, USES THEREOF AND RELATED KITS | Encodia, Inc. (US) | 2021-09-30 | — | — | WO | disclosed |
| WO-2020223133-A1 | METHODS AND REAGENTS FOR CLEAVAGE OF THE N-TERMINAL AMINO ACID FROM A POLYPEPTIDE | Encodia, Inc. (US) | 2020-11-05 | — | — | WO | disclosed |
| WO-2020198264-A1 | MODIFIED CLEAVASES, USES THEREOF AND RELATED KITS | Encodia, Inc. (US) | 2020-10-01 | — | — | WO | disclosed |