Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPSE | Q9Y251 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 5/20 | 0.39 |
| ▸ | MAOA | P21397 | 4/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CTSV | O60911 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | CTSC | P53634 | 1/20 | 0.37 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14372169 | 1.00 | HPSE (0.39) | HPSEMAOBMAOANSD2ABL1 | |
| SCHEMBL16950216 | 0.86 | MAOB (0.39) | HPSEMAOBMAOANSD2ABL1 | |
| SCHEMBL8539003 | 0.82 | TMEM97 (0.37) | HPSEMAOBMAOAGRM2LMNA | |
| SCHEMBL10703049 | 0.82 | TMEM97 (0.37) | HPSEMAOBMAOAGRM2LMNA | |
| SCHEMBL13013398 | 0.82 | TMEM97 (0.37) | HPSEMAOBMAOAGRM2LMNA | |
| SCHEMBL6853632 | 0.74 | TMEM97 (0.36) | HPSEMAOBMAOAGRM2LMNA | |
| SCHEMBL13868581 | 0.73 | HPSE (0.39) | HPSEMAOBHTTGRM2CTSV | |
| SCHEMBL17068328 | 0.72 | LMNA (0.37) | HPSEMAOBMAOAL3MBTL1GRM2 | |
| SCHEMBL6855778 | 0.72 | HPSE (0.34) | HPSEMAOBHTTGRM2LMNA | |
| SCHEMBL7973244 | 0.72 | HPSE (0.49) | HPSEMAOBMAOANSD2ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240261443-A1 | COMPOUNDS AND COMPOSITIONS USEFUL AS RADIOTRACERS FOR IMAGING OF REACTIVE OXIDATIVE SPECIES | UNIV WAKE FOREST HEALTH SCIENCES (US) | 2024-08-08 | — | — | US | disclosed |
| US-20200316229-A1 | COMPOUNDS AND COMPOSITIONS USEFUL AS RADIOTRACERS FOR IMAGING OF REACTIVE OXIDATIVE SPECIES | UNIV WAKE FOREST HEALTH SCIENCES (US) | 2020-10-08 | — | — | US | disclosed |
| US-20200316229-A1 | COMPOUNDS AND COMPOSITIONS USEFUL AS RADIOTRACERS FOR IMAGING OF REACTIVE OXIDATIVE SPECIES | UNIV WAKE FOREST HEALTH SCIENCES (US) | 2020-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200316229-A1 | COMPOUNDS AND COMPOSITIONS USEFUL AS RADIOTRACERS FOR IMAGING OF REACTIVE OXIDATIVE SPECIES | ROS1, GPX4, NOX4 | HPSE 3061/4885MAOB 376/4885MAOA 531/4885 |
| US-20240261443-A1 | COMPOUNDS AND COMPOSITIONS USEFUL AS RADIOTRACERS FOR IMAGING OF REACTIVE OXIDATIVE SPECIES | ROS1, GPX4, NOX4 | HPSE 3061/4885MAOB 376/4885MAOA 531/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.