Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9881101 | 0.82 | ALDH1A1 (0.42) | ALDH1A1HPGDHTTSMN1; SMN2LMNA | |
| SCHEMBL7293108 | 0.71 | ALDH1A1 (0.35) | ALDH1A1HPGDHTTSMN1; SMN2LMNA | |
| SCHEMBL3232505 | 0.71 | ALDH1A1 (0.35) | ALDH1A1HPGDHTTSMN1; SMN2LMNA | |
| SCHEMBL96749 | 0.71 | TSHR (0.44) | ALDH1A1HPGDSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7598649 | 0.71 | ALDH1A1 (0.61) | ALDH1A1HPGDHTTSMN1; SMN2LMNA | |
| SCHEMBL54889 | 0.71 | LMNA (0.47) | ALDH1A1HPGDHTTSMN1; SMN2LMNA | |
| SCHEMBL95849 | 0.71 | NFE2L2 (0.39) | ALDH1A1HPGDHTTSMN1; SMN2LMNA | |
| SCHEMBL5077616 | 0.71 | CA2 (0.50) | ALDH1A1HPGDSMN1; SMN2LMNAKMT2A | |
| SCHEMBL11124594 | 0.71 | ALDH1A1 (0.40) | ALDH1A1HPGDHTTSMN1; SMN2LMNA | |
| SCHEMBL1191551 | 0.71 | GRM4 (0.41) | ALDH1A1HPGDHTTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114956933-A | Marker containing isotope oxygen atom and preparation method and application thereof | 清华大学 | 2022-08-30 | — | — | CN | disclosed |
| EP-3388086-B1 | PSMA BINDING LIGAND-LINKER CONJUGATES AND METHODS FOR USING | PURDUE RESEARCH FOUNDATION (US) | 2020-10-07 | — | — | EP | disclosed |