Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9881101 | 0.82 | ALDH1A1 (0.42) | ALDH1A1HPGDHTTSMN1; SMN2LMNA | |
| SCHEMBL7855959 | 0.78 | ADRA2B (0.36) | ALDH1A1CA12CA1CA2CA4 | |
| SCHEMBL5139573 | 0.73 | ALDH1A1 (0.42) | ALDH1A1HPGDHTTSMN1; SMN2LMNA | |
| SCHEMBL3232505 | 0.71 | ALDH1A1 (0.35) | ALDH1A1HPGDHTTSMN1; SMN2LMNA | |
| SCHEMBL54889 | 0.71 | LMNA (0.47) | ALDH1A1HPGDHTTSMN1; SMN2LMNA | |
| SCHEMBL96749 | 0.71 | TSHR (0.44) | ALDH1A1HPGDSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7598649 | 0.71 | ALDH1A1 (0.61) | ALDH1A1HPGDHTTSMN1; SMN2LMNA | |
| SCHEMBL95849 | 0.71 | NFE2L2 (0.39) | ALDH1A1HPGDHTTSMN1; SMN2LMNA | |
| SCHEMBL22516396 | 0.71 | ALDH1A1 (0.35) | ALDH1A1HPGDHTTSMN1; SMN2LMNA | |
| SCHEMBL5077616 | 0.71 | CA2 (0.50) | ALDH1A1HPGDSMN1; SMN2LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691341-A | ANTILEUKEMIA AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5464833-A | Anticarcinogenic agents, antiretrovirus agents or autoimmune diseases | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-07 | — | — | US | disclosed |
| EP-0623598-A1 | APOPTOSIS REGULATOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-11-09 | — | — | EP | disclosed |
| US-4760064-A | Cardiotonic agent | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-07-26 | — | — | US | disclosed |
| EP-0112135-B1 | BROMINATION OF CEPHALOSPORINS | ELI LILLY AND COMPANY (US) | 1988-01-13 | — | — | EP | disclosed |
| EP-0187322-A1 | Carbostyril compounds, compositions containing same and processes for preparing same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-07-16 | — | — | EP | disclosed |
| US-4468514-A | Preparation of 3-bromocephalosporins from thiazoline azetidinones | ELI LILLY AND COMPANY (US) | 1984-08-28 | — | — | US | disclosed |
| EP-0112135-A2 | Bromination of cephalosporins | ELI LILLY AND COMPANY (US) | 1984-06-27 | — | — | EP | disclosed |