Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.40 |
| ▸ | P4HA1 | P13674 | 2/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.38 |
| ▸ | GABRE | P78334 | 1/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.38 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL185991 | 0.79 | P4HA1 (0.64) | NAPRTALDH1A1P4HTMP4HA1MIF | |
| SCHEMBL29760376 | 0.79 | NAPRT (0.72) | NAPRTSMN1; SMN2DGAT1GAARAB9A | |
| SCHEMBL29524968 | 0.79 | P4HA1 (0.64) | NAPRTALDH1A1P4HTMP4HA1MIF | |
| SCHEMBL30336313 | 0.79 | P4HTM (0.64) | NAPRTALDH1A1P4HTMP4HA1MIF | |
| SCHEMBL17801 | 0.79 | NAPRT (0.72) | NAPRTSMN1; SMN2DGAT1GAARAB9A | |
| SCHEMBL3196986 | 0.79 | P4HTM (0.64) | NAPRTALDH1A1P4HTMP4HA1MIF | |
| Hydrochloric Acid SCHEMBL2928501 | 0.77 | NAPRT (0.69) | NAPRTSMN1; SMN2DGAT1GAARAB9A | |
| SCHEMBL7336046 | 0.77 | P4HTM (0.54) | NAPRTALDH1A1P4HTMP4HA1MIF | |
| SCHEMBL24400225 | 0.77 | NAPRT (0.42) | NAPRTALDH1A1P4HTMP4HA1MIF | |
| SCHEMBL1092282 | 0.77 | KCNJ1 (0.47) | P4HTMP4HA1MIFSMN1; SMN2GABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6022974-A | Process for the production of 2-chloro-5-chloromethyl-pyridine | LONZA LTD. (CH) | 2000-02-08 | — | — | US | claimed |
| EP-0569947-B1 | Process for the production of 2-chloro-5-chloromethyl-pyridine | LONZA AG (CH) | 1995-03-01 | — | — | EP | claimed |
| JP-6032779-A | — | — | None | — | — | JP | disclosed |
| US-7994163-B2 | e.g. 3-tert-Butoxycarbonyl-7-chloro-6-chloromethyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine; serotonin receptor agonist; antidepressant, anxiolytic agent; obesity, obsessive compulsive disorder | ELI LILLY AND COMPANY (US) | 2011-08-09 | — | — | US | disclosed |
| US-7994163-B2 | e.g. 3-tert-Butoxycarbonyl-7-chloro-6-chloromethyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine; serotonin receptor agonist; antidepressant, anxiolytic agent; obesity, obsessive compulsive disorder | ELI LILLY AND COMPANY (US) | 2011-08-09 | — | — | US | disclosed |
| US-7994163-B2 | e.g. 3-tert-Butoxycarbonyl-7-chloro-6-chloromethyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine; serotonin receptor agonist; antidepressant, anxiolytic agent; obesity, obsessive compulsive disorder | ELI LILLY AND COMPANY (US) | 2011-08-09 | — | — | US | disclosed |
| EP-1924560-B1 | 6-SUBSTITUTED- 2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS | LILLY CO ELI (US) | 2009-08-05 | — | — | EP | disclosed |
| EP-1924560-B1 | 6-SUBSTITUTED- 2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS | LILLY CO ELI (US) | 2009-08-05 | — | — | EP | disclosed |
| WO-2009037542-A2 | SPIROCYCLIC COMPOUNDS AS STEAROYL COA DESATURASE INHIBITORS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-03-26 | — | — | WO | disclosed |
| US-20080255092-A1 | 6-Substituted-2,3,4,5-Tetrahydro-1H-Benzo[d]Azepines as 5-Ht2c Receptor Agonists | ELI LILLY AND COMPANY | 2008-10-16 | — | — | US | disclosed |
| US-20080255092-A1 | 6-Substituted-2,3,4,5-Tetrahydro-1H-Benzo[d]Azepines as 5-Ht2c Receptor Agonists | ELI LILLY AND COMPANY | 2008-10-16 | — | — | US | disclosed |
| WO-2001077078-A1 | NOVEL PYRIDONES AND THEIR USE AS MODULATORS OF SERINE HYDROLASE ENZYMES | DALHOUSIE UNIVERSITY (CA) | 2001-10-18 | — | — | WO | disclosed |
| US-6022974-A | Process for the production of 2-chloro-5-chloromethyl-pyridine | LONZA LTD. (CH) | 2000-02-08 | — | — | US | disclosed |
| US-6022974-A | Process for the production of 2-chloro-5-chloromethyl-pyridine | LONZA LTD. (CH) | 2000-02-08 | — | — | US | disclosed |
| JP-H0632779-A | PREPARATION OF 2-CHLORO-5-CHLOROMETHYL-PYRIDINE | LONZA AG | 1994-02-08 | — | — | JP | disclosed |
| EP-0569947-A1 | Process for the production of 2-chloro-5-chloromethyl-pyridine | LONZA AG (CH) | 1993-11-18 | — | — | EP | disclosed |
| US-4265892-A | Cephalosporins having an α-acylaminoacetic acid side chain | CIBA-GEIGY CORPORATION (US) | 1981-05-05 | — | — | US | disclosed |
| US-4154831-A | Cephalosporins having an α-acylaminoacetic acid side chain | CIBA-GEIGY CORPORATION (US) | 1979-05-15 | — | — | US | disclosed |
| US-4067979-A | Cephalosporins having an α-acyloxyacetic acid side chain | CIBA-GEIGY CORPORATION (US) | 1978-01-10 | — | — | US | disclosed |
| US-4041161-A | ANTIBIOTICS | CIBA-GEIGY CORPORATION (US) | 1977-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080255092-A1 | 6-Substituted-2,3,4,5-Tetrahydro-1H-Benzo[d]Azepines as 5-Ht2c Receptor Agonists | HTR2C, HTR3C, HTR3A | NAPRT 3996/4885ALDH1A1 957/4885P4HTM 2234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.