SCHEMBL3196986

SCHEMBL3196986

O=C(Cl)c1ccc(-c2ccc(C(=O)Cl)cn2)nc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P4HTM Q9NXG6 5/20 0.64
P4HA1 P13674 3/20 0.64
LDHA P00338 2/20 0.48
NAPRT Q6XQN6 1/20 0.48
RXFP1 Q9HBX9 2/20 0.44
NPC1 O15118 1/20 0.44
HPGDS O60760 3/20 0.42
BAZ2B Q9UIF8 1/20 0.42
MIF P14174 1/20 0.40
ALDH1A1 P00352 2/20 0.39
GABRP O00591 1/20 0.39
GABRD O14764 1/20 0.39
GABRA1 P14867 1/20 0.39
GABRB1 P18505 1/20 0.39
GABRG2 P18507 1/20 0.39
GABRB3 P28472 1/20 0.39
GABRA5 P31644 1/20 0.39
GABRA3 P34903 1/20 0.39
GABRA2 P47869 1/20 0.39
GABRB2 P47870 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30336313 1.00 P4HTM (0.64) P4HTMP4HA1LDHANAPRTRXFP1
SCHEMBL28576114 0.88 P4HTM (0.70) P4HTMP4HA1LDHANPC1HPGDS
SCHEMBL2551371 0.84 LDHA (0.73) P4HTMP4HA1LDHANAPRTRXFP1
SCHEMBL21480921 0.81 NPC1 (0.50) P4HTMP4HA1LDHARXFP1NPC1
SCHEMBL17801 0.81 NAPRT (0.72) NAPRTNPC1SMN1; SMN2
SCHEMBL29760376 0.81 NAPRT (0.72) NAPRTNPC1SMN1; SMN2
SCHEMBL6207143 0.80 DHODH (0.47) P4HTMP4HA1LDHANAPRTNPC1
SCHEMBL7336046 0.79 P4HTM (0.54) P4HTMP4HA1NAPRTNPC1MIF
Hydrochloric Acid SCHEMBL2928501 0.79 NAPRT (0.69) NAPRTNPC1SMN1; SMN2
SCHEMBL2255291 0.79 NAPRT (0.47) P4HTMP4HA1LDHANAPRTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230348665-A1 CHELATION CROSSLINKED POLYMERS, METHODS OF MAKING SAME, AND USES THEREOF CORNELL UNIVERSITY 2023-11-02 US claimed
EP-4188446-A1 CHELATION CROSSLINKED POLYMERS, METHODS OF MAKING SAME, AND USES THEREOF Cornell University (US) 2023-06-07 EP claimed
US-10177326-B2 Polymeric dielectrics, methods of manufacturing the same, and electronic devices and thin film transistors including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2019-01-08 US claimed
US-20170331057-A1 POLYMERIC DIELECTRICS, METHODS OF MANUFACTURING THE SAME, AND ELECTRONIC DEVICES AND THIN FILM TRANSISTORS INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2017-11-16 US claimed
US-20250296942-A1 Phosphonate-Based Coordination Complexes and Methods of Preparation and Use Thereof LOPEZ MEJIAS VILMALI (US) 2025-09-25 US disclosed
WO-2024221004-A2 MULTILAYERED PRODUCTS, METHODS OF MAKING SAME, AND USES THEREOF CORNELL UNIVERSITY (US) 2024-10-24 WO disclosed
WO-2023081474-A9 PHOSPHONATE-BASED COORDINATION COMPLEXES AND METHODS OF PREPARATION AND USE THEREOF UNIVERSITY OF PUERTO RICO (US) 2024-04-25 WO disclosed
US-20230348665-A1 CHELATION CROSSLINKED POLYMERS, METHODS OF MAKING SAME, AND USES THEREOF CORNELL UNIVERSITY 2023-11-02 US disclosed
EP-4188446-A1 CHELATION CROSSLINKED POLYMERS, METHODS OF MAKING SAME, AND USES THEREOF Cornell University (US) 2023-06-07 EP disclosed
WO-2023081474-A2 PHOSPHONATE-BASED COORDINATION COMPLEXES AND METHODS OF PREPARATION AND USE THEREOF UNIVERSITY OF PUERTO RICO (US) 2023-05-11 WO disclosed
US-11325110-B2 Magnetic Fe2O3 nanospheres with PNH surface modification and application hereof in water treatment SOOCHOW UNIVERSITY (CN) 2022-05-10 US disclosed
US-11325110-B2 Magnetic Fe2O3 nanospheres with PNH surface modification and application hereof in water treatment SOOCHOW UNIVERSITY (CN) 2022-05-10 US disclosed
US-7679082-B2 Multi-functional copolymers comprising rare earth metal complexes and devices thereof NATIONAL UNIVERSITY OF SINGAPORE (SG) 2010-03-16 US disclosed
CN-101128506-A Multifunctional copolymers containing rare earth metal complexes and devices thereof UNIV SINGAPORE (SG) 2008-02-20 CN disclosed
US-20070290199-A1 Multi-Functional Copolymers Comprising Rare Earth Metal Complexes and Devices Thereof NATIONAL UNIVERSITY OF SINGAPORE (SG) 2007-12-20 US disclosed
WO-2006052222-A2 MULTI-FUNCTIONAL COPOLYMERS COMPRISING RARE EARTH METAL COMPLEXES AND DEVICES THEREOF NATIONAL UNIVERSITY OF SINGAPORE (SG) 2006-05-18 WO disclosed
US-6114498-A Benzobisazole polymers containing 2,2'-bipyridine-5,5 '-diyl moieties THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 2000-09-05 US disclosed
US-5608059-A BIPYRIDINIUMS THAT CAN BE INCORPORATED IN ELECTROCHEMICAL OR OPTICAL SENSORS FOR ANION DETERMINATION EASTMAN KODAK COMPANY (US) 1997-03-04 US disclosed
EP-0647223-A1 ION-SENSITIVE BIPYRIDINE COMPLEXES KODAK LIMITED (GB) 1995-04-12 EP disclosed
WO-1994024123-A1 ION-SENSITIVE BIPYRIDINE COMPLEXES KODAK LIMITED (GB) 1994-10-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070290199-A1 Multi-Functional Copolymers Comprising Rare Earth Metal Complexes and Devices Thereof ZRANB2, BAZ1A, BAZ2B P4HTM 4724/4885P4HA1 2792/4885LDHA 3921/4885
US-20250296942-A1 Phosphonate-Based Coordination Complexes and Methods of Preparation and Use Thereof PHOSPHO1, PPIP5K2, INPP5B P4HTM 4279/4885P4HA1 4377/4885LDHA 3854/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.