Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 2/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29437212 | 1.00 | PDE4B (0.54) | PDE4BKDM4EPDE4DALDH1A1P2RY12 | |
| SCHEMBL29437215 | 1.00 | PDE4B (0.54) | PDE4BKDM4EPDE4DALDH1A1P2RY12 | |
| SCHEMBL22558028 | 0.85 | LMNA (0.40) | PDE4BKDM4ELMNAGAAHSD11B1 | |
| SCHEMBL29437214 | 0.85 | LMNA (0.40) | PDE4BKDM4ELMNAGAAHSD11B1 | |
| SCHEMBL29173091 | 0.83 | PDE4B (0.41) | PDE4BKDM4EALDH1A1MAPTHSD11B1 | |
| SCHEMBL1762554 | 0.80 | ALDH1A1 (0.47) | PDE4BKDM4EALDH1A1MAPTHSD11B1 | |
| SCHEMBL29372796 | 0.80 | ALDH1A1 (0.47) | PDE4BKDM4EALDH1A1MAPTHSD11B1 | |
| SCHEMBL22558034 | 0.77 | RAB9A (0.53) | PDE4BALDH1A1MAPTLMNAHSD11B1 | |
| SCHEMBL951462 | 0.77 | SMN1; SMN2 (0.52) | PDE4BKDM4EALDH1A1MAPTHSD11B1 | |
| SCHEMBL29558577 | 0.77 | ALDH1A1 (0.48) | PDE4BKDM4EALDH1A1MAPTHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3956314-A1 | PREPARATION OF SUBSTITUTED PYRAZOLES AND THEIR USE AS ANTHRANILAMIDES PRECURSORS | Adama Makhteshim Ltd. (IL) | 2022-02-23 | — | — | EP | disclosed |
| WO-2020212991-A1 | PREPARATION OF SUBSTITUTED PYRAZOLES AND THEIR USE AS ANTHRANILAMIDES PRECURSORS | ADAMA MAKHTESHIM LTD. (IL) | 2020-10-22 | — | — | WO | disclosed |