Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.31 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
| ▸ | CDK4 | P11802 | 1/20 | 0.30 |
| ▸ | CCND3 | P30281 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22562427 | 0.97 | CYP11B2 (0.36) | CYP11B2MAPTCYP11B1NR1H2NR1H3 | |
| SCHEMBL22562426 | 0.91 | CYP11B2 (0.36) | CYP11B2MAPTCYP11B1PDK2AR | |
| SCHEMBL22562492 | 0.89 | CYP11B2 (0.40) | CYP11B2CYP11B1PDK2HSD11B1PIM1 | |
| SCHEMBL22562331 | 0.88 | CYP11B2 (0.34) | CYP11B2MAPTNR1H2NR1H3HSD11B1 | |
| SCHEMBL22562601 | 0.86 | PTGDR2 (0.35) | CYP11B2MAPTCYP11B1NR1H2NR1H3 | |
| SCHEMBL22562624 | 0.86 | ALDH1A3 (0.35) | CYP11B2PDK2ALDH1A1L3MBTL1ENPP1 | |
| SCHEMBL22562491 | 0.86 | CYP11B2 (0.38) | CYP11B2CYP11B1ESR1PIM1CDK4 | |
| SCHEMBL22562497 | 0.85 | KIF11 (0.41) | CYP11B2ESR1GSK3BMEN1RAB9A | |
| SCHEMBL22562307 | 0.85 | CYP11B2 (0.35) | CYP11B2NR1H2NR1H3ARL3MBTL1 | |
| SCHEMBL22562217 | 0.85 | KDM4E (0.36) | CYP11B2MAPTCYP11B1ARALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3418278-B1 | ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC DEVICES | CYNORA GMBH (DE) | 2020-10-21 | — | — | EP | disclosed |