SCHEMBL22563486

SCHEMBL22563486

Cc1cc(C)nc(-c2cc(-n3c4ccccc4c4ccc(-c5cc(C(F)(F)F)cc(C(F)(F)F)c5)cc43)c(C#N)c(-n3c4ccccc4c4ccc(-c5cc(C(F)(F)F)cc(C(F)(F)F)c5)cc43)c2)n1

nearest known ligand 0.33

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.33
ABCG2 Q9UNQ0 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
METAP2 P50579 1/20 0.32
MEN1 O00255 1/20 0.31
CYP1A2 P05177 1/20 0.31
POLB P06746 1/20 0.31
CYP2C9 P11712 1/20 0.31
HPGD P15428 1/20 0.31
CYP2C19 P33261 1/20 0.31
KMT2A Q03164 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
CTSS P25774 1/20 0.31
CTSK P43235 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23487684 0.95 METAP2 (0.34) ABCG2L3MBTL1METAP2CTSSCTSK
SCHEMBL19919562 0.93 METAP2 (0.37) KIF11L3MBTL1METAP2POLBHPGD
SCHEMBL19942590 0.92 KIF11 (0.33) KIF11MEN1CYP1A2POLBCYP2C9
SCHEMBL22563510 0.90 KIF11 (0.43) KIF11ABCG2L3MBTL1MEN1POLB
SCHEMBL19909225 0.90 CTSS (0.37) KIF11METAP2MEN1CYP1A2POLB
SCHEMBL19903489 0.89 KIF11 (0.34) KIF11CYP1A2HPGDCYP2C19KMT2A
SCHEMBL23487679 0.89 ICMT (0.32) ABCG2L3MBTL1SMN1; SMN2CTSSCTSK
SCHEMBL19918048 0.89 KIF11 (0.38) KIF11L3MBTL1MEN1KMT2ASMN1; SMN2
SCHEMBL21279148 0.88 CTSS (0.34) KIF11L3MBTL1METAP2HPGDCTSS
SCHEMBL19909231 0.88 METAP2 (0.40) L3MBTL1METAP2POLBSMN1; SMN2CTSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210175434-A1 ORGANIC MOLECULES FOR USE IN ORGANIC OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2021-06-10 US disclosed
EP-3580300-B1 ORGANIC MOLECULES, ESPECIALLY FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2020-10-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210175434-A1 ORGANIC MOLECULES FOR USE IN ORGANIC OPTOELECTRONIC DEVICES OR10J3, OR51E2, OCIAD2 KIF11 3067/4885ABCG2 2612/4885L3MBTL1 3665/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.