SCHEMBL19909225

SCHEMBL19909225

Cc1cc(-c2cc(-n3c4ccccc4c4ccc(-c5cccc(C(F)(F)F)c5)cc43)c(C#N)c(-n3c4ccccc4c4ccc(-c5cc(C(F)(F)F)cc(C(F)(F)F)c5)cc43)c2)cc(C)n1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSS P25774 3/20 0.37
METAP2 P50579 1/20 0.35
KIF11 P52732 1/20 0.35
CTSK P43235 2/20 0.35
GRM5 P41594 1/20 0.35
POLB P06746 1/20 0.34
GRIN1 Q05586 4/20 0.34
GRIN2B Q13224 4/20 0.34
KMT2A Q03164 3/20 0.34
KDM4E B2RXH2 2/20 0.34
MEN1 O00255 1/20 0.34
NPC1 O15118 1/20 0.34
ATM Q13315 1/20 0.34
ALDH1A1 P00352 2/20 0.33
GAA P10253 2/20 0.33
ADORA1 P30542 1/20 0.33
XDH P47989 1/20 0.33
LMNA P02545 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19919562 0.96 METAP2 (0.37) CTSSMETAP2KIF11CTSKGRM5
SCHEMBL19909231 0.91 METAP2 (0.40) CTSSMETAP2CTSKGRM5POLB
SCHEMBL22563486 0.90 KIF11 (0.33) CTSSMETAP2KIF11CTSKPOLB
SCHEMBL19909195 0.89 KIF11 (0.45) METAP2KIF11GRM5POLBKMT2A
SCHEMBL19903651 0.88 AR (0.42) KIF11POLBALDH1A1ADORA1
SCHEMBL19918048 0.88 KIF11 (0.38) CTSSKIF11KMT2AKDM4EMEN1
SCHEMBL22562193 0.88 METAP2 (0.38) CTSSMETAP2KIF11CTSKKDM4E
SCHEMBL19913316 0.87 METAP2 (0.33) METAP2KIF11GRIN1GRIN2BADORA1
SCHEMBL21279148 0.87 CTSS (0.34) CTSSMETAP2KIF11CTSKKDM4E
SCHEMBL19917999 0.87 RXRA (0.37) KIF11KDM4EATMALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11588114-B2 Organic molecules for use in optoelectronic devices SAMSUNG DISPLAY CO., LTD. (KR) 2023-02-21 US disclosed
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2020-07-02 US disclosed
EP-3287451-A1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2018-02-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES OR10J3, OPRM1, OR51E2 CTSS 3907/4885METAP2 2365/4885KIF11 3067/4885
US-11588114-B2 Organic molecules for use in optoelectronic devices OR10J3, OPRM1, OR51E2 CTSS 3907/4885METAP2 2365/4885KIF11 3067/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.