SCHEMBL22563863

SCHEMBL22563863

CCc1cccc(N(N)C(=O)N(C)N)c1COc1ccn(-c2ccc(F)cc2)n1

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
NR1H4 Q96RI1 1/20 0.33
LMNA P02545 2/20 0.33
KMT2A Q03164 2/20 0.33
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
UBE2N P61088 2/20 0.32
MGLL Q99685 4/20 0.31
FAAH O00519 2/20 0.31
AGTR1 P30556 1/20 0.31
TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19909875 0.91 NR1H4 (0.37) KDM4ENR1H4LMNAKMT2ANPC1
SCHEMBL22563751 0.90 KDM4E (0.34) KDM4EL3MBTL1NR1H4LMNAKMT2A
SCHEMBL20845268 0.89 L3MBTL1 (0.37) KDM4EL3MBTL1LMNAKMT2ANPC1
SCHEMBL22563952 0.86 MGLL (0.33) KDM4EL3MBTL1NR1H4KMT2AMGLL
SCHEMBL22563938 0.85 NR1H4 (0.35) KDM4ENR1H4KMT2ANPC1RAB9A
SCHEMBL22564019 0.83 NR1H4 (0.33) NR1H4
SCHEMBL22564123 0.81 NR1H4 (0.36) KDM4ENR1H4LMNAKMT2A
SCHEMBL22563756 0.81 DGAT1 (0.34) L3MBTL1NR1H4LMNAKMT2ANPC1
SCHEMBL19909868 0.80 ALDH1A1 (0.35) L3MBTL1NR1H4KMT2ANPC1RAB9A
SCHEMBL22563771 0.79 NR1H4 (0.33) NR1H4LMNANPC1RAB9ATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2841429-B1 TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES SUMITOMO CHEMICAL CO (JP) 2020-10-21 EP disclosed