Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20902038 | 0.90 | NR1H4 (0.35) | NR1H4KAT6A | |
| SCHEMBL22564091 | 0.90 | NR1H4 (0.38) | NR1H4KMT2ACACNA2D1TSHRPOLB | |
| SCHEMBL22564154 | 0.89 | NR1H4 (0.37) | NR1H4KMT2ARXRAGRIN1GRIN2B | |
| SCHEMBL22564024 | 0.88 | NR1H4 (0.36) | NR1H4TSHRHPGDPOLBALDH1A1 | |
| SCHEMBL22563918 | 0.87 | SIGMAR1 (0.40) | NR1H4KMT2APOLBKDM4EMEN1 | |
| SCHEMBL22563773 | 0.85 | KLKB1 (0.32) | CACNA2D1POLBKDM4EALDH1A1 | |
| SCHEMBL20902007 | 0.85 | ALDH1A1 (0.41) | NR1H4KMT2APOLBKDM4EALDH1A1 | |
| SCHEMBL19909882 | 0.85 | NR1H4 (0.33) | NR1H4TP53ALDH1A1 | |
| SCHEMBL22563772 | 0.85 | KDM4E (0.34) | NR1H4CACNA2D1ADORA3ADORA2AKDM4E | |
| SCHEMBL22563758 | 0.85 | UBE2N (0.35) | NR1H4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2841429-B1 | TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES | SUMITOMO CHEMICAL CO (JP) | 2020-10-21 | — | — | EP | disclosed |