Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.43 |
| ▸ | CA2 | P00918 | 5/20 | 0.43 |
| ▸ | CA9 | Q16790 | 5/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL343985 | 0.88 | ALDH1A1 (0.50) | CA12CA2CA9PTGS2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7568273 | 0.86 | ALDH1A1 (0.48) | CA12CA2CA9PTGS2ALDH1A1 | |
| SCHEMBL9620534 | 0.84 | HSD17B10 (0.52) | CA12CA2CA9PTGS2PTGS1 | |
| SCHEMBL20251135 | 0.79 | RAB9A (0.50) | PTGS2PTGS1ALDH1A1MAPTNPC1 | |
| SCHEMBL20251140 | 0.79 | RAB9A (0.50) | PTGS2PTGS1ALDH1A1MAPTNPC1 | |
| SCHEMBL48732 | 0.76 | POLB (0.64) | CA12CA2CA9ALDH1A1MAPT | |
| SCHEMBL48731 | 0.76 | POLB (0.64) | CA12CA2CA9ALDH1A1MAPT | |
| SCHEMBL42344 | 0.74 | NPC1 (0.69) | CA12CA2CA9PTGS2PTGS1 | |
| SCHEMBL15704429 | 0.74 | CA2 (0.69) | CA12CA2CA9PTGS2ALDH1A1 | |
| SCHEMBL42343 | 0.74 | NPC1 (0.69) | CA12CA2CA9PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200333349-A1 | SIGNALING CONJUGATES AND METHODS OF USE | VENTANA MED SYST INC (US) | 2020-10-22 | — | — | US | disclosed |