Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRG2 | P18507 | 3/20 | 0.54 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.54 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.54 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.54 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 2/20 | 0.53 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.51 |
| ▸ | GRM5 | P41594 | 4/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | KDM1A | O60341 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | ATR | Q13535 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31384802 | 0.82 | GABRG2 (0.52) | GABRG2GABRB3GABRA5GABRA3GABRA1 | |
| SCHEMBL5653453 | 0.78 | NPC1 (0.50) | GABRG2GABRB3GABRA5GABRA3GABRA1 | |
| SCHEMBL3422474 | 0.77 | ADRA2C (0.60) | GABRG2GABRB3GABRA5GABRA3GABRA1 | |
| SCHEMBL31272452 | 0.77 | ADRA2C (0.60) | GABRG2GABRB3GABRA5GABRA3GABRA1 | |
| SCHEMBL9792939 | 0.76 | CLK4 (0.62) | GABRG2GABRB3GABRA5GABRA3GABRA1 | |
| SCHEMBL10431256 | 0.76 | GABRA1 (0.59) | GABRG2GABRB3GABRA5GABRA3GABRA1 | |
| SCHEMBL16016610 | 0.75 | GABRG2 (0.63) | GABRG2GABRB3GABRA5GABRA3GABRA1 | |
| SCHEMBL385924 | 0.75 | ATR (0.62) | GABRG2GABRB3GABRA5GABRA3GABRA1 | |
| SCHEMBL1133442 | 0.75 | CLK4 (0.66) | IDO1CLK4GRM5ALDH1A1TSHR | |
| SCHEMBL29472032 | 0.75 | CLK4 (0.66) | IDO1CLK4GRM5ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220209141-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2022-06-30 | — | — | US | disclosed |
| WO-2020212296-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2020-10-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220209141-A1 | METAL COMPLEXES | AP1M1, SOD1, AP3M1 | GABRG2 2314/4885GABRB3 2117/4885GABRA5 2149/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.