Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | G6PD | P11413 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | FPR1 | P21462 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22555808 | 1.00 | ALDH1A1 (0.36) | ALDH1A1KDM4EHPGDHSD17B10BRD4 | |
| SCHEMBL22567440 | 0.85 | HSD11B1 (0.36) | ALDH1A1GAACACNA1BAPBA1POLB | |
| SCHEMBL22555775 | 0.85 | HSD11B1 (0.36) | ALDH1A1GAACACNA1BAPBA1POLB | |
| SCHEMBL20907904 | 0.83 | HSD11B1 (0.41) | ALDH1A1KDM4EHPGDGAAL3MBTL1 | |
| SCHEMBL22555738 | 0.83 | HSD11B1 (0.41) | ALDH1A1KDM4EHPGDGAAL3MBTL1 | |
| SCHEMBL20898345 | 0.81 | ALDH1A1 (0.39) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL22567520 | 0.80 | LMNA (0.43) | ALDH1A1HPGDGAAL3MBTL1LMNA | |
| SCHEMBL20898249 | 0.80 | LMNA (0.43) | ALDH1A1HPGDGAAL3MBTL1LMNA | |
| SCHEMBL22555792 | 0.80 | LMNA (0.43) | ALDH1A1HPGDGAAL3MBTL1LMNA | |
| SCHEMBL22567345 | 0.80 | LMNA (0.43) | ALDH1A1HPGDGAAL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11325915-B2 | Lysyl oxidase inhibitors | THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) | 2022-05-10 | — | — | US | disclosed |
| US-20200331922-A1 | LYSYL OXIDASE INHIBITORS | THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) | 2020-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200331922-A1 | LYSYL OXIDASE INHIBITORS | LOXL1, LOXL2, LOXL3 | ALDH1A1 1199/4885KDM4E 974/4885HPGD 403/4885 |
| US-11325915-B2 | Lysyl oxidase inhibitors | LOXL1, LOXL2, LOXL3 | ALDH1A1 1199/4885KDM4E 974/4885HPGD 403/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.