Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9932456 | 0.84 | RAB9A (0.49) | RAB9APTPN1LTA4HNPC1LMNA | |
| SCHEMBL1121619 | 0.78 | ALDH1A1 (0.52) | RAB9APTPN1NPC1HTR7MEN1 | |
| SCHEMBL27904192 | 0.75 | NAPRT (0.47) | POLBMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL2645324 | 0.74 | LTA4H (0.58) | RAB9APTPN1LTA4HNPC1HTR7 | |
| SCHEMBL30416407 | 0.74 | CCNC (0.47) | MEN1KMT2AALDH1A1MAPTL3MBTL1 | |
| Hydrochloric Acid SCHEMBL5253545 | 0.72 | LTA4H (0.56) | RAB9APTPN1LTA4HNPC1HTR7 | |
| SCHEMBL10906842 | 0.72 | RAB9A (0.65) | RAB9APTPN1LTA4HNPC1CYP11B1 | |
| SCHEMBL6282620 | 0.72 | GAA (0.57) | RAB9ALMNAPOLBCYP11B1CYP11B2 | |
| SCHEMBL1993655 | 0.70 | L3MBTL1 (0.58) | RAB9APTPN1LTA4HNPC1LMNA | |
| SCHEMBL20517285 | 0.70 | CCNC (0.41) | RAB9ANPC1CYP11B1CYP11B2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220227735-A1 | THERAPEUTIC METHODS AND COMPOUNDS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2022-07-21 | — | — | US | disclosed |
| WO-2020219591-A1 | THERAPEUTIC METHODS AND COMPOUNDS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2020-10-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220227735-A1 | THERAPEUTIC METHODS AND COMPOUNDS | REN, FURIN, QTRT1 | RAB9A 259/4885PTPN1 3471/4885LTA4H 3380/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.