Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | AGXT | P21549 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | DRD2 | P14416 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.51 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.51 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.50 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.50 |
| ▸ | PRKDC | P78527 | 2/20 | 0.50 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.50 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | FYN | P06241 | 1/20 | 0.50 |
| ▸ | KIF11 | P52732 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32211602 | 1.00 | KMO (0.60) | KMOLMNAAGXTKMT2AMEN1 | |
| SCHEMBL20696085 | 0.98 | KMO (0.58) | KMOLMNAAGXTKMT2AMEN1 | |
| SCHEMBL27329825 | 0.86 | LMNA (0.71) | KMOLMNAAGXTKMT2AMEN1 | |
| SCHEMBL9723025 | 0.86 | DRD2 (0.68) | LMNAKMT2AMEN1DRD2MAPT | |
| Phenol SCHEMBL28278427 | 0.84 | LMNA (0.76) | KMOLMNAAGXTKMT2AMEN1 | |
| SCHEMBL1599836 | 0.82 | MEN1 (0.60) | LMNAAGXTKMT2AMEN1DRD2 | |
| SCHEMBL29774627 | 0.82 | MEN1 (0.60) | LMNAAGXTKMT2AMEN1DRD2 | |
| SCHEMBL29914690 | 0.82 | MEN1 (0.60) | LMNAAGXTKMT2AMEN1DRD2 | |
| SCHEMBL17144785 | 0.82 | MEN1 (0.60) | LMNAAGXTKMT2AMEN1DRD2 | |
| SCHEMBL28278426 | 0.81 | HPGD (0.57) | KMOLMNAAGXTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 308 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118791322-B | Carbon nanowire/porous glass carbon composite material and preparation method thereof | 湖南德智新材料有限公司 | 2024-11-15 | — | — | CN | claimed |
| CN-118791322-A | Carbon nanowire/porous glass carbon composite material and preparation method thereof | 湖南德智新材料有限公司 | 2024-10-18 | — | — | CN | claimed |
| EP-1870084-B1 | Composition for dyeing keratin fibres comprising 2,3-diamino-6,7-dihydro-1H,5H-pyrazolo[1,2-a]pyrazol-1-one, 6-chloro 2-methyl 5-aminophenol and a substituted meta-aminophenol | ORÉAL L (FR) | 2015-07-22 | — | — | EP | claimed |
| EP-1870085-B1 | Composition for dyeing keratinous fibres comprising 2,3-diamino-6,7-dihydro-1H,5H-pyrazolo[1,2-a]pyrazol-1-one, para-phenylenediamine or para-toluenediamine and a substituted meta-aminophenol | ORÉAL L (FR) | 2015-07-22 | — | — | EP | claimed |
| EP-2350090-B1 | SPIRO-OXINDOLE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC (CA) | 2015-06-03 | — | — | EP | claimed |
| US-8263606-B2 | Spiro-oxindole compounds and their use as therapeutic agents | XENON PHARMACEUTICALS INC. (CA) | 2012-09-11 | — | — | US | claimed |
| EP-2350090-A2 | SPIRO-OXINDOLE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | Xenon Pharmaceuticals Inc. (CA) | 2011-08-03 | — | — | EP | claimed |
| US-20100137299-A1 | SPIRO-OXINDOLE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2010-06-03 | — | — | US | claimed |
| WO-2010045251-A2 | SPIRO-OXINDOLE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS, INC. (CA) | 2010-04-22 | — | — | WO | claimed |
| US-7651537-B2 | Composition for dyeing keratin fibers, comprising 2,3-diamino-6,7-dihydro-1H,5H-pyrazolo[1,2-a]pyrazol-1-one, 6-chloro-2-methyl-5-aminophenol and a substituted meta-aminophenol | L'OREAL S.A. (FR) | 2010-01-26 | — | — | US | claimed |
| US-20040205903-A1 | Dyeing composition comprising a cationic pyrrolidine-based para-phenylenefiamine, a tertiary para-phenylenediamine and a benzomorpholine coupler, methods and uses | L'OREAL (FR) | 2004-10-21 | — | — | US | claimed |
| US-20040139561-A1 | Composition of the dyeing of human hair | KPSS - KAO PROFESSIONAL SALON SERVICES GMBH (DE) | 2004-07-22 | — | — | US | claimed |
| EP-1428503-A2 | Composition for the dyeing of human hair | KPSS-Kao Professional Salon Services GmbH (DE) | 2004-06-16 | — | — | EP | claimed |
| EP-1428502-A2 | Composition for the dyeing of human hair | KPSS-Kao Professional Salon Services GmbH (DE) | 2004-06-16 | — | — | EP | claimed |
| US-20040107514-A1 | Composition for the dyeing of human hair | KPSS - KAO PROFESSIONAL SALON SERVICES GMBH (DE) | 2004-06-10 | — | — | US | claimed |
| US-20040003474-A1 | Composition for the dyeing of human hair | KPSS - KAO PROFESSIONAL SALON SERVICES GMBH (DE) | 2004-01-08 | — | — | US | claimed |
| EP-1378228-A1 | Composition for the dyeing of human hair | KPSS-Kao Professional Salon Services GmbH (DE) | 2004-01-07 | — | — | EP | claimed |
| US-20030040639-A1 | Method for the preparation of substituted benzene derivatives | H. LUNDBECK A/S (DK) | 2003-02-27 | — | — | US | claimed |
| EP-1246819-A1 | A METHOD FOR THE PREPARATION OF SUBSTITUTED BENZENE DERIVATIVES | H. Lundbeck A/S (DK) | 2002-10-09 | — | — | EP | claimed |
| WO-2001049681-A1 | A METHOD FOR THE PREPARATION OF SUBSTITUTED BENZENE DERIVATIVES | H. LUNDBECK A/S (DK) | 2001-07-12 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040205903-A1 | Dyeing composition comprising a cationic pyrrolidine-based para-phenylenefiamine, a tertiary para-phenylenediamine and a benzomorpholine coupler, methods and uses | CDC73, KRT18, PAH | KMO 28/4885LMNA 962/4885AGXT 3199/4885 |
| US-20030040639-A1 | Method for the preparation of substituted benzene derivatives | SCLY, CBR3, TST | KMO 340/4885LMNA 1034/4885AGXT 2385/4885 |
| US-20100137299-A1 | SPIRO-OXINDOLE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | TRPV3, TRPV1, TRPC3 | KMO 1191/4885LMNA 1296/4885AGXT 3193/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.