Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 9/20 | 0.36 |
| ▸ | EPAS1 | Q99814 | 9/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8902134 | 0.67 | HIF1A (0.39) | HIF1AEPAS1PPARGKDM4ENPC1 | |
| SCHEMBL20124031 | 0.66 | MAOA (0.42) | KDM4ENPC1ALDH1A1MAPTHPGD | |
| SCHEMBL9475843 | 0.64 | ALDH1A1 (0.45) | HIF1AEPAS1KDM4ENPC1CA12 | |
| SCHEMBL9092301 | 0.64 | HIF1A (0.48) | HIF1AEPAS1ALDH1A1HPGD | |
| SCHEMBL1748567 | 0.63 | HTR2C (0.49) | HIF1AEPAS1KDM4ENPC1CA12 | |
| SCHEMBL29644871 | 0.63 | HTR2C (0.49) | HIF1AEPAS1KDM4ENPC1CA12 | |
| SCHEMBL3049240 | 0.62 | ALDH1A1 (0.46) | HIF1AEPAS1KDM4ENPC1CA12 | |
| SCHEMBL7738844 | 0.62 | HIF1A (0.58) | HIF1AEPAS1KDM4ENPC1CA12 | |
| SCHEMBL9092974 | 0.62 | HIF1A (0.46) | HIF1AEPAS1KDM4ENPC1CA12 | |
| SCHEMBL9092213 | 0.62 | HIF1A (0.44) | HIF1AEPAS1KDM4ENPC1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020215481-A1 | APPLICATIONS OF PSORALEN IN PREPARING NRF2 INHIBITOR, MEDICAMENT FOR NRF2 INHIBITION-RELATED DISEASES, AND ANTICANCER MEDICAMENT | 广东省中医院 | 2020-10-29 | — | — | WO | disclosed |