Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.88 |
| ▸ | MEN1 | O00255 | 6/20 | 0.88 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.88 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.88 |
| ▸ | LMNA | P02545 | 9/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.68 |
| ▸ | HTT | P42858 | 5/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.68 |
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12218179 | 0.86 | SMN1; SMN2 (0.66) | SMN1; SMN2MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL17522785 | 0.82 | SMN1; SMN2 (0.78) | SMN1; SMN2MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL22610058 | 0.77 | HSD17B10 (0.97) | SMN1; SMN2MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL20145409 | 0.76 | TTR (0.69) | SMN1; SMN2MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL9011652 | 0.76 | DRD2 (0.65) | MEN1KMT2AGAA | |
| SCHEMBL9011831 | 0.76 | DRD2 (0.65) | MEN1KMT2AGAA | |
| SCHEMBL17522787 | 0.75 | SMN1; SMN2 (0.69) | SMN1; SMN2MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL11401119 | 0.75 | SMN1; SMN2 (0.62) | SMN1; SMN2MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL3805304 | 0.74 | DRD2 (0.68) | SMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL15828247 | 0.71 | TTR (0.71) | SMN1; SMN2MEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11213518-B2 | Ligands of the mu, kappa, and delta opioid receptors | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2022-01-04 | — | — | US | claimed |
| US-20200345715-A1 | Ligands of the Mu, Kappa, and Delta Opioid Receptors | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2020-11-05 | — | — | US | claimed |
| US-11213518-B2 | Ligands of the mu, kappa, and delta opioid receptors | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2022-01-04 | — | — | US | disclosed |
| US-11213518-B2 | Ligands of the mu, kappa, and delta opioid receptors | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2022-01-04 | — | — | US | disclosed |
| US-20200345715-A1 | Ligands of the Mu, Kappa, and Delta Opioid Receptors | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2020-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11213518-B2 | Ligands of the mu, kappa, and delta opioid receptors | OPRK1, OPRD1, OPRM1 | SMN1; SMN2 2910/4885MEN1 4884/4885KMT2A 3716/4885 |
| US-20200345715-A1 | Ligands of the Mu, Kappa, and Delta Opioid Receptors | OPRK1, OPRD1, OPRM1 | SMN1; SMN2 2910/4885MEN1 4884/4885KMT2A 3716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.