Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.97 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.97 |
| ▸ | LMNA | P02545 | 7/20 | 0.97 |
| ▸ | MAPT | P10636 | 6/20 | 0.97 |
| ▸ | HTT | P42858 | 4/20 | 0.97 |
| ▸ | TSHR | P16473 | 1/20 | 0.97 |
| ▸ | RECQL | P46063 | 1/20 | 0.97 |
| ▸ | MEN1 | O00255 | 5/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.78 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.78 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.78 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.78 |
| ▸ | HPGD | P15428 | 1/20 | 0.78 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.78 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.70 |
| ▸ | GAA | P10253 | 1/20 | 0.68 |
| ▸ | TTR | P02766 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17522789 | 0.94 | SMN1; SMN2 (0.97) | HSD17B10SMN1; SMN2LMNAMAPTHTT | |
| SCHEMBL15158388 | 0.80 | TTR (1.00) | HSD17B10SMN1; SMN2LMNAMAPTHTT | |
| SCHEMBL19801754 | 0.80 | SMN1; SMN2 (0.72) | HSD17B10SMN1; SMN2LMNAMAPTHTT | |
| SCHEMBL22610055 | 0.77 | SMN1; SMN2 (0.88) | HSD17B10SMN1; SMN2LMNAMAPTHTT | |
| SCHEMBL9808080 | 0.76 | ALDH1A1 (0.62) | HSD17B10SMN1; SMN2LMNAMAPTHTT | |
| SCHEMBL20145409 | 0.74 | TTR (0.69) | HSD17B10SMN1; SMN2LMNAMAPTHTT | |
| SCHEMBL11401119 | 0.73 | SMN1; SMN2 (0.62) | HSD17B10SMN1; SMN2LMNAMAPTHTT | |
| SCHEMBL11679951 | 0.72 | CYP2D6 (0.61) | HSD17B10SMN1; SMN2LMNAMAPTHTT | |
| SCHEMBL12301158 | 0.72 | LMNA (0.56) | HSD17B10SMN1; SMN2LMNAMAPTHTT | |
| SCHEMBL22207292 | 0.71 | ALDH1A1 (0.58) | HSD17B10SMN1; SMN2LMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11213518-B2 | Ligands of the mu, kappa, and delta opioid receptors | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2022-01-04 | — | — | US | claimed |
| US-20200345715-A1 | Ligands of the Mu, Kappa, and Delta Opioid Receptors | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2020-11-05 | — | — | US | claimed |
| US-11213518-B2 | Ligands of the mu, kappa, and delta opioid receptors | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2022-01-04 | — | — | US | disclosed |
| US-11213518-B2 | Ligands of the mu, kappa, and delta opioid receptors | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2022-01-04 | — | — | US | disclosed |
| US-20200345715-A1 | Ligands of the Mu, Kappa, and Delta Opioid Receptors | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2020-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11213518-B2 | Ligands of the mu, kappa, and delta opioid receptors | OPRK1, OPRD1, OPRM1 | HSD17B10 3910/4885SMN1; SMN2 2910/4885LMNA 3856/4885 |
| US-20200345715-A1 | Ligands of the Mu, Kappa, and Delta Opioid Receptors | OPRK1, OPRD1, OPRM1 | HSD17B10 3910/4885SMN1; SMN2 2910/4885LMNA 3856/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.