Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.43 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15888238 | 0.84 | SMN1; SMN2 (0.55) | LMNASMN1; SMN2CYP1A2CYP2C19NPC1 | |
| SCHEMBL14793682 | 0.83 | SMN1; SMN2 (0.48) | LMNASMN1; SMN2CYP1A2CYP2C19NPC1 | |
| SCHEMBL15888179 | 0.81 | SMN1; SMN2 (0.53) | LMNASMN1; SMN2CYP1A2CYP2C19NPC1 | |
| SCHEMBL22621227 | 0.81 | SMN1; SMN2 (0.48) | LMNASMN1; SMN2CYP1A2CYP2C19NPC1 | |
| SCHEMBL22398380 | 0.78 | SLC7A5 (0.49) | KDM4ELMNASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL31865 | 0.78 | SMN1; SMN2 (0.49) | LMNASMN1; SMN2CYP1A2CYP2C19NPC1 | |
| SCHEMBL10706157 | 0.76 | L3MBTL1 (0.57) | LMNASMN1; SMN2CYP1A2CYP2C19NPC1 | |
| SCHEMBL15888240 | 0.76 | NPSR1 (0.52) | LMNASMN1; SMN2CYP1A2CYP2C19NPC1 | |
| SCHEMBL14007283 | 0.75 | LTA4H (0.46) | KDM4ELMNACYP1A2CYP2C19MEN1 | |
| SCHEMBL28553022 | 0.75 | SMN1; SMN2 (0.52) | KDM4ELMNASMN1; SMN2CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200347011-A1 | DOUBLE-HEADED PROTEASE INHIBITOR | UBE INDUSTRIES, LTD. (JP) | 2020-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200347011-A1 | DOUBLE-HEADED PROTEASE INHIBITOR | TMPRSS15, SPINT2, PRSS2 | KDM4E 4002/4885LMNA 1038/4885SMN1; SMN2 3255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.