Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | TLR2 | O60603 | 1/20 | 0.38 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16355779 | 0.88 | SLC7A5 (0.55) | SLC7A5LOXL2HIF1ACYP4F2CYP4A11 | |
| SCHEMBL7611802 | 0.81 | SLC7A5 (0.58) | SLC7A5LOXL2HIF1ACYP4F2CYP4A11 | |
| SCHEMBL15876029 | 0.81 | SLC7A5 (0.54) | SLC7A5LOXL2HIF1ACYP4F2CYP4A11 | |
| SCHEMBL16355834 | 0.81 | SLC7A5 (0.57) | SLC7A5LOXL2HIF1ACYP4F2CYP4A11 | |
| Hydrochloric Acid SCHEMBL17433718 | 0.80 | SLC7A5 (0.53) | SLC7A5SMN1; SMN2LOXL2HIF1ACYP4F2 | |
| SCHEMBL557761 | 0.79 | MEP1B (0.51) | SLC7A5SMN1; SMN2HIF1AMEP1B | |
| SCHEMBL22621036 | 0.78 | KDM4E (0.48) | KDM4EALDH1A1MAPK1LMNAKMT2A | |
| SCHEMBL16355830 | 0.78 | SLC7A5 (0.56) | SLC7A5SMN1; SMN2LOXL2HIF1ACYP4F2 | |
| SCHEMBL16923863 | 0.78 | LOXL2 (0.43) | SLC7A5KDM4EALDH1A1SMN1; SMN2LOXL2 | |
| SCHEMBL20025383 | 0.76 | GLS (0.38) | KDM4EALDH1A1GAAMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200347011-A1 | DOUBLE-HEADED PROTEASE INHIBITOR | UBE INDUSTRIES, LTD. (JP) | 2020-11-05 | — | — | US | disclosed |
| EP-3705471-A1 | DOUBLE-HEADED PROTEASE INHIBITOR | UBE Industries, Ltd. (JP) | 2020-09-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200347011-A1 | DOUBLE-HEADED PROTEASE INHIBITOR | TMPRSS15, SPINT2, PRSS2 | SLC7A5 690/4885KDM4E 4002/4885ALDH1A1 1685/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.