Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A1 | P54219 | 1/20 | 0.54 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.54 |
| ▸ | RAD52 | P43351 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | HSD17B3 | P37058 | 3/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | ALB | P02768 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24623266 | 0.87 | RAD52 (0.48) | SLC18A1SLC18A2RAD52ALDH1A1KDM4E | |
| SCHEMBL24623582 | 0.87 | RAD52 (0.48) | SLC18A1SLC18A2RAD52ALDH1A1KDM4E | |
| SCHEMBL22632306 | 0.86 | MTNR1B (0.53) | SLC18A1SLC18A2RAD52ALDH1A1KDM4E | |
| SCHEMBL24623269 | 0.84 | RAD52 (0.45) | SLC18A1SLC18A2RAD52ALDH1A1KDM4E | |
| SCHEMBL22632229 | 0.79 | SLC18A1 (0.50) | SLC18A1SLC18A2ALDH1A1KDM4EPOLB | |
| SCHEMBL22632227 | 0.76 | SLC18A1 (0.59) | SLC18A1SLC18A2ALDH1A1KDM4EHPGD | |
| SCHEMBL22632085 | 0.74 | ALDH1A1 (0.69) | SLC18A1SLC18A2ALDH1A1KDM4EPOLB | |
| SCHEMBL22632087 | 0.74 | CYP2D6 (0.76) | ALDH1A1KDM4EHPGDHSD17B10CYP2D6 | |
| SCHEMBL15082514 | 0.70 | HSD17B3 (0.72) | ALDH1A1KDM4EHPGDCASP1CASP7 | |
| SCHEMBL29360977 | 0.70 | SLC18A1 (1.00) | SLC18A1SLC18A2ALDH1A1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020223174-A1 | COUMARIN-MODIFIED ANDROGENS FOR THE TREATMENT OF PROSTATE CANCER | HEALTH RESEARCH, INC. (US) | 2020-11-05 | — | — | WO | disclosed |