Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 3/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.53 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | SLC18A1 | P54219 | 1/20 | 0.47 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24623269 | 0.89 | RAD52 (0.45) | MTNR1BMTNR1ARAD52SLC18A1SLC18A2 | |
| SCHEMBL22632088 | 0.86 | SLC18A1 (0.54) | RAD52SLC18A1SLC18A2ATMMEN1 | |
| SCHEMBL24623266 | 0.83 | RAD52 (0.48) | RAD52SLC18A1SLC18A2ATMMEN1 | |
| SCHEMBL24623582 | 0.83 | RAD52 (0.48) | RAD52SLC18A1SLC18A2ATMMEN1 | |
| SCHEMBL22632228 | 0.81 | MTNR1A (0.58) | MTNR1BMTNR1ASLC18A1SLC18A2ATM | |
| SCHEMBL22632226 | 0.78 | MTNR1B (0.60) | MTNR1BMTNR1ASLC18A1SLC18A2ATM | |
| SCHEMBL22632089 | 0.77 | ALDH1A1 (0.67) | MTNR1BMTNR1ASLC18A1SLC18A2ATM | |
| SCHEMBL22632322 | 0.76 | MTNR1A (0.82) | MTNR1BMTNR1AATMMEN1KMT2A | |
| SCHEMBL22632307 | 0.72 | MTNR1A (0.53) | MTNR1BMTNR1ASLC18A1SLC18A2KDM4E | |
| SCHEMBL15082514 | 0.70 | HSD17B3 (0.72) | KMT2ACA12CA9KDM4EHSD17B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020223174-A1 | COUMARIN-MODIFIED ANDROGENS FOR THE TREATMENT OF PROSTATE CANCER | HEALTH RESEARCH, INC. (US) | 2020-11-05 | — | — | WO | disclosed |