Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A1 | P54219 | 1/20 | 1.00 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 1.00 |
| ▸ | HSD17B3 | P37058 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30603352 | 0.99 | SLC18A1 (0.97) | SLC18A1SLC18A2HSD17B3ALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL27082363 | 0.99 | SLC18A1 (0.97) | SLC18A1SLC18A2HSD17B3ALDH1A1GAA | |
| SCHEMBL14669803 | 0.82 | SLC18A1 (0.70) | SLC18A1SLC18A2HSD17B3ALDH1A1GAA | |
| SCHEMBL24865523 | 0.81 | SLC18A1 (0.67) | SLC18A1SLC18A2HSD17B3ALDH1A1GAA | |
| SCHEMBL24832744 | 0.81 | SLC18A1 (0.67) | SLC18A1SLC18A2HSD17B3ALDH1A1GAA | |
| SCHEMBL24832802 | 0.80 | HSD17B3 (0.68) | SLC18A1SLC18A2HSD17B3ALDH1A1GAA | |
| SCHEMBL14527910 | 0.79 | SLC18A1 (0.65) | SLC18A1SLC18A2HSD17B3ALDH1A1GAA | |
| SCHEMBL19398068 | 0.79 | LCK (0.66) | SLC18A1SLC18A2HSD17B3ALDH1A1GAA | |
| SCHEMBL12433414 | 0.78 | HSD17B3 (0.73) | SLC18A1SLC18A2HSD17B3ALDH1A1GAA | |
| SCHEMBL4209990 | 0.75 | SLC18A1 (0.60) | SLC18A1SLC18A2HSD17B3ALDH1A1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025096017-A2 | VESICULAR NEUROTRANSMITTER LEAKAGE ASSAY | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2025-05-08 | — | — | WO | claimed |
| US-20250345365-A1 | TREATMENT OF NEURONAL DISEASES | CENTER FOR EXCELLENCE IN BRAIN SCIENCE AND INTELLIGENCE TECH CHINESE ACADEMY OF SCIENCES (CN) | 2025-11-13 | — | — | US | disclosed |
| WO-2025096017-A2 | VESICULAR NEUROTRANSMITTER LEAKAGE ASSAY | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2025-05-08 | — | — | WO | disclosed |
| CN-119735674-A | Anti-VMAT 2 antibodies or antigen binding fragments thereof, compositions and uses thereof | 合肥综合性国家科学中心大健康研究院 | 2025-04-01 | — | — | CN | disclosed |
| US-20240150372-A1 | OXA-IBOGAINE ANALOGUES FOR TREATMENT OF SUBSTANCE USE DISORDERS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2024-05-09 | — | — | US | disclosed |
| CN-117750954-A | Oxa-ibogine analogues for the treatment of substance use disorders | 纽约哥伦比亚大学董事会 | 2024-03-22 | — | — | CN | disclosed |
| EP-4294388-A1 | OXA-IBOGAINE ANALOGUES FOR TREATMENT OF SUBSTANCE USE DISORDERS | The Trustees Of Columbia University In The City Of New York (US) | 2023-12-27 | — | — | EP | disclosed |
| EP-4288048-A1 | OXA-IBOGAINE INSPIRED ANALOGUES FOR TREATMENT OF NEUROLOGICAL AND PSYCHIATRIC DISORDERS | The Trustees Of Columbia University In The City Of New York (US) | 2023-12-13 | — | — | EP | disclosed |
| US-20230382919-A1 | OXA- IBOGAINE INSPIRED ANALOGUES FOR TREATMENT OF NEUROLOGICAL AND PSYCHIATRIC DISORDERS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2023-11-30 | — | — | US | disclosed |
| CN-117120050-A | Oxa-ibogine inspired analogues for the treatment of neurological and psychiatric disorders | 纽约哥伦比亚大学董事会 | 2023-11-24 | — | — | CN | disclosed |
| US-20230348465-A1 | IBOGAINE ANALOGS AS THERAPEUTICS FOR NEUROLOGICAL AND PSYCHIATRIC DISORDERS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2023-11-02 | — | — | US | disclosed |
| CN-116940348-A | Meckel cell activator, enhancer for synaptic vesicle, neurotransmitter release promoter, method for evaluating neurotransmitter release activity of Meckel cell, and method for screening neurotransmitter release promoter of Meckel cell | 株式会社资生堂 | 2023-10-24 | — | — | CN | disclosed |
| EP-4185578-A1 | IBOGAINE ANALOGS AS THERAPEUTICS FOR NEUROLOGICAL AND PSYCHIATRIC DISORDERS | The Trustees Of Columbia University In The City Of New York (US) | 2023-05-31 | — | — | EP | disclosed |
| WO-2022202714-A1 | MERKEL CELL ACTIVATOR, SYNAPTIC VESICLE ENHANCER, NEUROTRANSMITTER RELEASE ACCELERATOR, METHOD FOR ASSESSING NEUROTRANSMITTER RELEASE ACTIVITY OF MERKEL CELLS, AND METHOD FOR SCREENING FOR NEUROTRANSMITTER RELEASE ACCELERATOR FOR MERKEL CELLS | 株式会社 資生堂 | 2022-09-29 | — | — | WO | disclosed |
| US-20220273726-A1 | TREATMENT OF NEURONAL DISEASES | CENTER FOR EXCELLENCE IN BRAIN SCIENCE AND INTELLIGENCE TECHNOLOGY, CHINESE ACADEMY OF SCIENCES (CN) | 2022-09-01 | — | — | US | disclosed |
| WO-2022178099-A1 | OXA-IBOGAINE ANALOGUES FOR TREATMENT OF SUBSTANCE USE DISORDERS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2022-08-25 | — | — | WO | disclosed |
| WO-2022170268-A1 | OXA-IBOGAINE INSPIRED ANALOGUES FOR TREATMENT OF NEUROLOGICAL AND PSYCHIATRIC DISORDERS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2022-08-11 | — | — | WO | disclosed |
| EP-4039801-A1 | APPLICATION OF PTBP1 INHIBITOR IN PREVENTING AND/OR TREATING NERVOUS SYSTEM DISEASE RELATED TO FUNCTIONAL NEURONAL DEATH | CENTER FOR EXCELLENCE IN BRAIN SCIENCE AND INTELLIGENCE TECHNOLOGY, CHINESE ACADEMY OF SCIENCES (CN) | 2022-08-10 | — | — | EP | disclosed |
| WO-2022020352-A1 | IBOGAINE ANALOGS AS THERAPEUTICS FOR NEUROLOGICAL AND PSYCHIATRIC DISORDERS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2022-01-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230348465-A1 | IBOGAINE ANALOGS AS THERAPEUTICS FOR NEUROLOGICAL AND PSYCHIATRIC DISORDERS | CHRNA3, CHRNB3, CHRNA4 | SLC18A1 385/4885SLC18A2 99/4885HSD17B3 1394/4885 |
| US-20240150372-A1 | OXA-IBOGAINE ANALOGUES FOR TREATMENT OF SUBSTANCE USE DISORDERS | OPRD1, OPRM1, OPRK1 | SLC18A1 290/4885SLC18A2 51/4885HSD17B3 297/4885 |
| US-20230382919-A1 | OXA- IBOGAINE INSPIRED ANALOGUES FOR TREATMENT OF NEUROLOGICAL AND PSYCHIATRIC DISORDERS | GRIA4, GRIA3, GRIN3A | SLC18A1 1145/4885SLC18A2 183/4885HSD17B3 431/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.