Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A1 | P54219 | 1/20 | 0.50 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.47 |
| ▸ | HSD17B3 | P37058 | 4/20 | 0.47 |
| ▸ | IGLV6-57 | P01721 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.45 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24623256 | 0.86 | IGLV6-57 (0.46) | SLC18A1SLC18A2CYP2D6HSD17B3IGLV6-57 | |
| SCHEMBL22632228 | 0.85 | MTNR1A (0.58) | SLC18A1SLC18A2CYP2D6HSD17B3IGLV6-57 | |
| SCHEMBL6689431 | 0.83 | HSD17B3 (0.62) | CYP2D6HSD17B3IGLV6-57ALDH1A1GAA | |
| SCHEMBL24623285 | 0.82 | ALDH1A1 (0.44) | SLC18A1SLC18A2CYP2D6HSD17B3IGLV6-57 | |
| SCHEMBL22632227 | 0.81 | SLC18A1 (0.59) | SLC18A1SLC18A2CYP2D6HSD17B3ALDH1A1 | |
| SCHEMBL6417463 | 0.80 | ALDH1A1 (0.60) | CYP2D6HSD17B3IGLV6-57ALDH1A1GAA | |
| SCHEMBL2627650 | 0.79 | KDM4E (0.50) | CYP2D6HSD17B3ALDH1A1GAAHPGD | |
| SCHEMBL22632088 | 0.79 | SLC18A1 (0.54) | SLC18A1SLC18A2CYP2D6HSD17B3ALDH1A1 | |
| SCHEMBL22632087 | 0.78 | CYP2D6 (0.76) | CYP2D6ALDH1A1GAAHPGDKDM4E | |
| SCHEMBL10878198 | 0.78 | HSD17B3 (0.65) | HSD17B3IGLV6-57ALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020223174-A1 | COUMARIN-MODIFIED ANDROGENS FOR THE TREATMENT OF PROSTATE CANCER | HEALTH RESEARCH, INC. (US) | 2020-11-05 | — | — | WO | disclosed |