Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.58 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.47 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.47 |
| ▸ | HSD17B3 | P37058 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.44 |
| ▸ | SLC18A1 | P54219 | 1/20 | 0.43 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24623285 | 0.87 | ALDH1A1 (0.44) | MTNR1AMTNR1BALDH1A1KDM4EMAPT | |
| SCHEMBL22632229 | 0.85 | SLC18A1 (0.50) | ALDH1A1KDM4EMAPTHPGDNPC1 | |
| SCHEMBL22632226 | 0.82 | MTNR1B (0.60) | MTNR1AMTNR1BALDH1A1KDM4EHPGD | |
| SCHEMBL24623256 | 0.81 | IGLV6-57 (0.46) | ALDH1A1KDM4EMAPTHPGDNPC1 | |
| SCHEMBL2627659 | 0.81 | LCK (0.51) | ALDH1A1KDM4EMAPTHPGDNPC1 | |
| SCHEMBL22632306 | 0.81 | MTNR1B (0.53) | MTNR1AMTNR1BALDH1A1KDM4EHPGD | |
| SCHEMBL22632322 | 0.81 | MTNR1A (0.82) | MTNR1AMTNR1BALDH1A1KDM4EHPGD | |
| SCHEMBL2633118 | 0.79 | KDM4E (0.47) | ALDH1A1KDM4EMAPTHPGDNPC1 | |
| SCHEMBL13326331 | 0.79 | ALDH1A1 (0.46) | ALDH1A1KDM4EMAPTHPGDNPC1 | |
| SCHEMBL6689431 | 0.79 | HSD17B3 (0.62) | ALDH1A1KDM4EMAPTHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020223174-A1 | COUMARIN-MODIFIED ANDROGENS FOR THE TREATMENT OF PROSTATE CANCER | HEALTH RESEARCH, INC. (US) | 2020-11-05 | — | — | WO | disclosed |