Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.34 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13747792 | 0.76 | NOS3 (0.42) | GABRA1GABRB2LMNAGAAGABRG2 | |
| SCHEMBL2558474 | 0.75 | MCHR1 (0.42) | KMT2AMEN1LMNAGAATSHR | |
| SCHEMBL29324813 | 0.75 | MAOA (0.43) | GABRA1GABRB2LMNAGAAGABRG2 | |
| SCHEMBL15617285 | 0.75 | GABRA1 (0.40) | GABRA1GABRB2LMNAGAAGABRG2 | |
| SCHEMBL11172021 | 0.74 | MEN1 (0.43) | KMT2AMEN1LMNACYP1A2CYP3A4 | |
| SCHEMBL21332905 | 0.73 | CYP1A2 (0.56) | KMT2AMEN1LMNAGAACYP1A2 | |
| SCHEMBL9711233 | 0.71 | KDM4E (0.38) | KMT2AGABRA1GABRB2LMNAGAA | |
| SCHEMBL249080 | 0.71 | MEN1 (0.41) | KMT2AMEN1LMNABLML3MBTL1 | |
| SCHEMBL28048096 | 0.71 | RAB9A (0.42) | KMT2AMEN1LMNAGAACYP1A2 | |
| SCHEMBL4808650 | 0.71 | GABRA1 (0.48) | GABRA1GABRB2LMNAGABRG2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020225330-A1 | DHODH INHIBITORS AND THEIR USE AS ANTIVIRAL AGENTS | UNIVERSITÄT HAMBURG (DE) | 2020-11-12 | — | — | WO | disclosed |